Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 4/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.50 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.50 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.50 |
| ▸ | ALB | P02768 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 1/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30468820 | 0.87 | SLC7A5 (0.55) | SLC7A5TAAR1SLC6A2ESR1PTGS1 | |
| SCHEMBL12864780 | 0.85 | KMT2A (0.55) | ESR1PTGS1PTGS2LMNACYP2C9 | |
| SCHEMBL15222219 | 0.85 | KMT2A (0.55) | ESR1PTGS1PTGS2LMNACYP2C9 | |
| SCHEMBL5511480 | 0.84 | SLC1A3 (0.63) | SLC7A5PTGS1FOLH1ACESLC1A3 | |
| SCHEMBL883357 | 0.84 | SLC1A3 (0.63) | SLC7A5PTGS1FOLH1ACESLC1A3 | |
| SCHEMBL25132188 | 0.83 | PTGS1 (0.58) | ESR1PTGS1PTGS2LMNACYP2C9 | |
| SCHEMBL11551473 | 0.83 | PPARG (0.51) | SLC6A2ESR1PTGS1PTGS2LMNA | |
| SCHEMBL21261466 | 0.83 | TAAR1 (0.55) | SLC7A5TAAR1SLC6A2ESR1ESR2 | |
| SCHEMBL12184990 | 0.83 | TAAR1 (0.55) | SLC7A5TAAR1SLC6A2ESR1ESR2 | |
| SCHEMBL12873863 | 0.83 | CPB2 (0.49) | SLC7A5ESR1PTGS1PTGS2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230047816-A1 | PFKFB3 INHIBITORS AND THEIR USES | GERO PTE. LTD. (SG) | 2023-02-16 | — | — | US | disclosed |
| WO-2021195183-A1 | COMPOSITIONS AND METHODS FOR INHIBITING PROTEIN EMBRYONIC ECTODERM DEVELOPMENT ACTIVITY AND TREATING DISEASE | EXO THERAPEUTICS, INC. (US) | 2021-09-30 | — | — | WO | disclosed |
| US-20210284621-A1 | CANNABINOIDS AND USES THEREOF | CORBUS PHARMACEUTICALS, INC. | 2021-09-16 | — | — | US | disclosed |
| WO-2019104851-A4 | BETA-HYDROXYBUTYRYL-AMINO ACID COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 刘成 | 2019-08-15 | — | — | WO | disclosed |
| US-9145425-B2 | Cephem compound having catechol group | SHIONOGI & CO., LTD. (JP) | 2015-09-29 | — | — | US | disclosed |
| US-9115083-B2 | Compounds from Antrodia cinnamomea and use thereof | SIMPSON BIOTECH CO., LTD. (TW) | 2015-08-25 | — | — | US | disclosed |
| US-8883773-B2 | Cephem compound having pseudo-catechol group | SHIONOGI & CO., LTD. (JP) | 2014-11-11 | — | — | US | disclosed |
| US-20140179753-A1 | COMPOUNDS FROM ANTRODIA CINNAMOMEA AND USE THEREOF | SIMPSON BIOTECH CO., LTD. (TW) | 2014-06-26 | — | — | US | disclosed |
| US-8703968-B2 | Compounds from Antrodia cinnamomea and use thereof | SIMPSON BIOTECH CO., LTD. (TW) | 2014-04-22 | — | — | US | disclosed |
| US-20130225649-A1 | COMPOUNDS FROM ANTRODIA CINNAMOMEA AND USE THEREOF | SIMPSON BIOTECH CO., LTD. (TW) | 2013-08-29 | — | — | US | disclosed |
| US-20130102583-A1 | CEPHEM COMPOUND HAVING CATECHOL GROUP | SHIONOGI & CO., LTD. (JP) | 2013-04-25 | — | — | US | disclosed |
| US-20130079319-A1 | CEPHEM COMPOUND HAVING PSEUDO-CATECHOL GROUP | SHIONOGI & CO., LTD. (JP) | 2013-03-28 | — | — | US | disclosed |
| US-20100179140-A1 | INDENOISOQUINOLINONE ANALOGS AND METHODS OF USE THEREOF | INOTEK PHARMACEUTICALS CORPORATION (US) | 2010-07-15 | — | — | US | disclosed |
| US-20100137294-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING INVERTEBRATE PESTS | GENETIC TECHNOLOGIES LIMITED (AU) | 2010-06-03 | — | — | US | disclosed |
| US-20100121049-A1 | INDENOISOQUINOLINONE ANALOGS AND METHODS OF USE THEREOF | INOTEK PHARMACEUTICALS CORPORATION (US) | 2010-05-13 | — | — | US | disclosed |
| US-7652028-B2 | Indenoisoquinolinone analogs and methods of use thereof | INOTEK PHARMACEUTICALS CORPORATION (US) | 2010-01-26 | — | — | US | disclosed |
| US-20070049555-A1 | Indenoisoquinolinone analogs and methods of use thereof | INOTEK PHARMACEUTICALS CORPORATION (US) | 2007-03-01 | — | — | US | disclosed |
| EP-1313559-A4 | RECYCLABLE METATHESIS CATALYSTS | TRUSTEES BOSTON COLLEGE (US) | 2004-02-04 | — | — | EP | disclosed |
| EP-1313559-A2 | RECYCLABLE METATHESIS CATALYSTS | Trustees of Boston College (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002014376-A2 | RECYCLABLE METATHESIS CATALYSTS | TRUSTEES OF BOSTON COLLEGE (US) | 2002-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130079319-A1 | CEPHEM COMPOUND HAVING PSEUDO-CATECHOL GROUP | CENPE, CCNE2, CEP170 | SLC7A5 65/4885TAAR1 3338/4885SLC6A2 252/4885 |
| US-20210284621-A1 | CANNABINOIDS AND USES THEREOF | CNR2, CNR1, FAAH | SLC7A5 4783/4885TAAR1 579/4885SLC6A2 1644/4885 |
| US-20230047816-A1 | PFKFB3 INHIBITORS AND THEIR USES | PFKFB3, PFKFB4, PFKFB1 | SLC7A5 2902/4885TAAR1 4862/4885SLC6A2 3140/4885 |
| US-20130225649-A1 | COMPOUNDS FROM ANTRODIA CINNAMOMEA AND USE THEREOF | HAVCR2, CYP51A1, NPC1 | SLC7A5 3463/4885TAAR1 4151/4885SLC6A2 3164/4885 |
| US-20100137294-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING INVERTEBRATE PESTS | PPP1R10, TASP1, PPP5C | SLC7A5 4173/4885TAAR1 1561/4885SLC6A2 4122/4885 |
| US-20130102583-A1 | CEPHEM COMPOUND HAVING CATECHOL GROUP | COMT, EZH1, SETD7 | SLC7A5 33/4885TAAR1 3869/4885SLC6A2 236/4885 |
| US-20070049555-A1 | Indenoisoquinolinone analogs and methods of use thereof | TNNI3, IDH2, GLS | SLC7A5 4773/4885TAAR1 4267/4885SLC6A2 2111/4885 |
| US-20100121049-A1 | INDENOISOQUINOLINONE ANALOGS AND METHODS OF USE THEREOF | TNNI3, IDH2, GLS | SLC7A5 4773/4885TAAR1 4267/4885SLC6A2 2111/4885 |
| US-20100179140-A1 | INDENOISOQUINOLINONE ANALOGS AND METHODS OF USE THEREOF | TNNI3, IDH2, GLS | SLC7A5 4773/4885TAAR1 4267/4885SLC6A2 2111/4885 |
| US-20140179753-A1 | COMPOUNDS FROM ANTRODIA CINNAMOMEA AND USE THEREOF | HAVCR2, CYP51A1, NPC1 | SLC7A5 3463/4885TAAR1 4151/4885SLC6A2 3164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.