Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 5/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.35 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 2/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL65865 | 0.81 | CES2 (0.36) | KIF11ACHECA1CA2CA9 | |
| SCHEMBL15568688 | 0.69 | KIF11 (0.55) | KIF11ACHECA1CA2CA9 | |
| Silver SCHEMBL6115105 | 0.69 | KIF11 (0.55) | KIF11ACHECA1CA2CA9 | |
| Potassium Ion SCHEMBL28729147 | 0.69 | KIF11 (0.55) | KIF11ACHECA1CA2CA9 | |
| SCHEMBL64465 | 0.67 | CES2 (0.31) | KIF11CES2 | |
| SCHEMBL6466449 | 0.66 | ALDH1A1 (0.34) | KIF11CA1CA2CA9CA12 | |
| SCHEMBL64311 | 0.64 | PTPN1 (0.33) | ACHE | |
| Lithium Ion SCHEMBL16563208 | 0.64 | KIF11 (0.50) | KIF11ACHECA1CA2CA9 | |
| SCHEMBL1666979 | 0.63 | KIF11 (0.59) | KIF11ACHECA1CA2CA9 | |
| SCHEMBL3151057 | 0.63 | KIF11 (0.59) | KIF11ACHECA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8558012-B2 | 2-fluoro-1,3-benzodithiol 1,1,3,3-tetraoxide derivative, production method thereof, and production method of monofluoromethyl group-containing compound using the same | NAGOYA INSTITUTE OF TECHNOLOGY (JP) | 2013-10-15 | — | — | US | claimed |
| US-8558012-B2 | 2-fluoro-1,3-benzodithiol 1,1,3,3-tetraoxide derivative, production method thereof, and production method of monofluoromethyl group-containing compound using the same | NAGOYA INSTITUTE OF TECHNOLOGY (JP) | 2013-10-15 | — | — | US | disclosed |
| US-8207184-B2 | Condensation compound between fluorinated cyclopentane ring and aromatic ring, and process for producing the same | SUMITOMO CHEMICAL CO., LTD. (JP) | 2012-06-26 | — | — | US | disclosed |
| US-8129400-B2 | Condensation compound between fluorinated cyclopentane ring and aromatic ring, and process for producing the same | SUMITOMO CHEMICAL CO., LTD. (JP) | 2012-03-06 | — | — | US | disclosed |
| US-20110319637-A1 | 2-FLUORO-1,3-BENZODITHIOL 1,1,3,3-TETRAOXIDE DERIVATIVE, PRODUCTION METHOD THEREOF, AND PRODUCTION METHOD OF MONOFLUOROMETHYL GROUP-CONTAINING COMPOUND USING THE SAME | NAGOYA INSTITUTE OF TECHNOLOGY (JP) | 2011-12-29 | — | — | US | disclosed |
| US-20110282073-A1 | CONDENSATION COMPOUND BETWEEN FLUORINATED CYCLOPENTANE RING AND AROMATIC RING, AND PROCESS FOR PRODUCING THE SAME | SUMITOMO CHEMICAL CO., LTD. (JP) | 2011-11-17 | — | — | US | disclosed |
| US-20110213162-A1 | CONDENSATION COMPOUND BETWEEN FLUORINATED CYCLOPENTANE RING AND AROMATIC RING, AND PROCESS FOR PRODUCING THE SAME | SUMITOMO CHEMICAL CO., LTD. (JP) | 2011-09-01 | — | — | US | disclosed |
| US-8008336-B2 | Forming electronic material, semiconductors | SUMITOMO CHEMICAL CO., LTD. (JP) | 2011-08-30 | — | — | US | disclosed |
| US-7638654-B2 | 1-fluoro-1, 1-bis-(phenylsulfonyl)methane and production method thereof | NAGOYA INSTITUTE OF TECHNOLOGY (JP) | 2009-12-29 | — | — | US | disclosed |
| US-20090131723-A1 | 1-Fluoro-1,1-Bis-(Phenylsulfonyl)Methane and Production Method Thereof | TOSOH F-TECH, INC. (JP) | 2009-05-21 | — | — | US | disclosed |
| US-6040339-A | TREATMENT AND PROPHYLAXIS OF HYPERCHOLESTEREMIA OR ARTERIOSCLEROSIS IN A MAMMAL | SANKYO COMPANY, LIMITED (JP) | 2000-03-21 | — | — | US | disclosed |
| EP-0526849-B1 | Substituted N-Fluoropyridiniumsulfonate, intermediates therefor and preparation processes thereof | DAIKIN IND LTD (JP) | 1999-12-01 | — | — | EP | disclosed |
| EP-0948073-A1 | ELECTROLYTIC SOLUTION AND DEVICE FOR GENERATING ELECTRIC ENERGY THEREWITH | Daikin Industries, Ltd. (JP) | 1999-10-06 | — | — | EP | disclosed |
| US-5880147-A | Amide derivatives having ACAT inhibitory activity, their preparation and their therapeutic and prohylactic use | SANKYO COMPANY, LIMITED (JP) | 1999-03-09 | — | — | US | disclosed |
| EP-0646979-B1 | MATERIAL FOR GENERATING ELECTRIC ENERGY | DAIKIN IND LTD (JP) | 1998-11-11 | — | — | EP | disclosed |
| EP-0763524-A1 | Urea and amide derivatives having ACAT inhibitory activity, their preparation and their therapeutic and prophylactic use | SANKYO COMPANY LIMITED (JP) | 1997-03-19 | — | — | EP | disclosed |
| US-5573868-A | ELECTROCHEMICAL REACTION BETWEEN A COMPOUND HAVING A N-F BOND AND ELECTRON DONOR | DAIKIN INDUSTRIES, LTD. (JP) | 1996-11-12 | — | — | US | disclosed |
| EP-0646979-A1 | MATERIAL FOR GENERATING ELECTRIC ENERGY | DAIKIN INDUSTRIES, LTD. (JP) | 1995-04-05 | — | — | EP | disclosed |
| US-5374732-A | Chemical intermediates as fluorination agents | DAIKIN INDUSTRIES, LTD. (JP) | 1994-12-20 | — | — | US | disclosed |
| EP-0526849-A1 | Novel substituted N-Fluoropyridiniumsulfonate, intermediates therefor and preparation processes thereof | DAIKIN INDUSTRIES, LTD. (JP) | 1993-02-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319637-A1 | 2-FLUORO-1,3-BENZODITHIOL 1,1,3,3-TETRAOXIDE DERIVATIVE, PRODUCTION METHOD THEREOF, AND PRODUCTION METHOD OF MONOFLUOROMETHYL GROUP-CONTAINING COMPOUND USING THE SAME | CBR1, CYP1B1, CYP2F1 | KIF11 2204/4885ACHE 3512/4885CA1 2728/4885 |
| US-20110213162-A1 | CONDENSATION COMPOUND BETWEEN FLUORINATED CYCLOPENTANE RING AND AROMATIC RING, AND PROCESS FOR PRODUCING THE SAME | RCC1, AFF4, TPR | KIF11 859/4885ACHE 3434/4885CA1 1537/4885 |
| US-20110282073-A1 | CONDENSATION COMPOUND BETWEEN FLUORINATED CYCLOPENTANE RING AND AROMATIC RING, AND PROCESS FOR PRODUCING THE SAME | RCC1, AFF4, TPR | KIF11 859/4885ACHE 3434/4885CA1 1537/4885 |
| US-20090131723-A1 | 1-Fluoro-1,1-Bis-(Phenylsulfonyl)Methane and Production Method Thereof | CYP2S1, ARSA, MSMO1 | KIF11 3771/4885ACHE 3720/4885CA1 3020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.