Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.30 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.30 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL64466 | 0.82 | ACP1 (0.35) | CES2 | |
| SCHEMBL64311 | 0.73 | PTPN1 (0.33) | — | |
| SCHEMBL7917534 | 0.69 | — | — | |
| SCHEMBL65864 | 0.67 | KIF11 (0.39) | CES2KIF11 | |
| Lithium Ion SCHEMBL9617535 | 0.65 | CES2 (0.46) | CES2ALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL21522541 | 0.65 | CES2 (0.46) | CES2ALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL21522571 | 0.65 | CES2 (0.46) | CES2ALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL21522648 | 0.65 | CES2 (0.46) | CES2ALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL28713750 | 0.65 | CES2 (0.46) | CES2ALDH1A1CYP3A4HPGDALOX15 | |
| Trifluoromethanesulfonic Acid SCHEMBL8717313 | 0.62 | ACHE (0.40) | CES2KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8558012-B2 | 2-fluoro-1,3-benzodithiol 1,1,3,3-tetraoxide derivative, production method thereof, and production method of monofluoromethyl group-containing compound using the same | NAGOYA INSTITUTE OF TECHNOLOGY (JP) | 2013-10-15 | — | — | US | claimed |
| EP-1720836-B1 | 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO [D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | LILLY CO ELI (US) | 2014-04-16 | — | — | EP | disclosed |
| US-8580780-B2 | 6 substituted 2, 3,4,5 tetrahydro-1H-benzo[d]azepines as 5-HT2C receptor agonist | ELI LILLY AND COMPANY (US) | 2013-11-12 | — | — | US | disclosed |
| US-8558012-B2 | 2-fluoro-1,3-benzodithiol 1,1,3,3-tetraoxide derivative, production method thereof, and production method of monofluoromethyl group-containing compound using the same | NAGOYA INSTITUTE OF TECHNOLOGY (JP) | 2013-10-15 | — | — | US | disclosed |
| EP-2479168-A1 | 6-Substituted 2,3,4,5-Tetrahydro-1H-Benzo [d]Azepines as 5-HT2C Receptor Agonists | ELI LILLY AND COMPANY (US) | 2012-07-25 | — | — | EP | disclosed |
| US-8207184-B2 | Condensation compound between fluorinated cyclopentane ring and aromatic ring, and process for producing the same | SUMITOMO CHEMICAL CO., LTD. (JP) | 2012-06-26 | — | — | US | disclosed |
| US-8129400-B2 | Condensation compound between fluorinated cyclopentane ring and aromatic ring, and process for producing the same | SUMITOMO CHEMICAL CO., LTD. (JP) | 2012-03-06 | — | — | US | disclosed |
| US-20120028961-A1 | 6 Substituted 2, 3,4,5 Tetrahydro-1H-Benzo[d]Azepines as 5-HT2c Receptor Agonist | ELI LILLY AND COMPANY (US) | 2012-02-02 | — | — | US | disclosed |
| US-20110319637-A1 | 2-FLUORO-1,3-BENZODITHIOL 1,1,3,3-TETRAOXIDE DERIVATIVE, PRODUCTION METHOD THEREOF, AND PRODUCTION METHOD OF MONOFLUOROMETHYL GROUP-CONTAINING COMPOUND USING THE SAME | NAGOYA INSTITUTE OF TECHNOLOGY (JP) | 2011-12-29 | — | — | US | disclosed |
| US-20110282073-A1 | CONDENSATION COMPOUND BETWEEN FLUORINATED CYCLOPENTANE RING AND AROMATIC RING, AND PROCESS FOR PRODUCING THE SAME | SUMITOMO CHEMICAL CO., LTD. (JP) | 2011-11-17 | — | — | US | disclosed |
| US-6531460-B1 | Vitamin D3 derivatives | TEIJIN LIMITED (JP) | 2003-03-11 | — | — | US | disclosed |
| US-20020132799-A1 | Vitamin D3 dervative and treating agent for inflammatory respiratory disease using same | TEIJIN LIMITED | 2002-09-19 | — | — | US | disclosed |
| US-20020103173-A1 | Vitamin D3 derivative and treating agent for inflammatory respiratory disease using same | TEIJIN LIMITED | 2002-08-01 | — | — | US | disclosed |
| US-20020099039-A1 | Vitamin D3 derivative and treating agent for inflammatory respiratory disease using same | TEIJIN LIMITED | 2002-07-25 | — | — | US | disclosed |
| US-20020091109-A1 | Vitamin D3 derivative and treating agent for inflammatory respiratory disease using same | TEIJIN LIMITED | 2002-07-11 | — | — | US | disclosed |
| EP-1123921-A1 | VITAMIN D 3? DERIVATIVES AND REMEDIES FOR INFLAMMATORY RESPIRATORY DISEASES CONTAINING THE SAME | TEIJIN LIMITED (JP) | 2001-08-16 | — | — | EP | disclosed |
| EP-0526849-B1 | Substituted N-Fluoropyridiniumsulfonate, intermediates therefor and preparation processes thereof | DAIKIN IND LTD (JP) | 1999-12-01 | — | — | EP | disclosed |
| EP-0948073-A1 | ELECTROLYTIC SOLUTION AND DEVICE FOR GENERATING ELECTRIC ENERGY THEREWITH | Daikin Industries, Ltd. (JP) | 1999-10-06 | — | — | EP | disclosed |
| US-5374732-A | Chemical intermediates as fluorination agents | DAIKIN INDUSTRIES, LTD. (JP) | 1994-12-20 | — | — | US | disclosed |
| EP-0526849-A1 | Novel substituted N-Fluoropyridiniumsulfonate, intermediates therefor and preparation processes thereof | DAIKIN INDUSTRIES, LTD. (JP) | 1993-02-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020103173-A1 | Vitamin D3 derivative and treating agent for inflammatory respiratory disease using same | CYP24A1, VDR, CYP2R1 | CES2 4844/4885ALDH1A1 800/4885CYP3A4 944/4885 |
| US-20110319637-A1 | 2-FLUORO-1,3-BENZODITHIOL 1,1,3,3-TETRAOXIDE DERIVATIVE, PRODUCTION METHOD THEREOF, AND PRODUCTION METHOD OF MONOFLUOROMETHYL GROUP-CONTAINING COMPOUND USING THE SAME | CBR1, CYP1B1, CYP2F1 | CES2 231/4885ALDH1A1 160/4885CYP3A4 36/4885 |
| US-20020132799-A1 | Vitamin D3 dervative and treating agent for inflammatory respiratory disease using same | CYP24A1, VDR, CYP2R1 | CES2 4863/4885ALDH1A1 696/4885CYP3A4 1436/4885 |
| US-20110282073-A1 | CONDENSATION COMPOUND BETWEEN FLUORINATED CYCLOPENTANE RING AND AROMATIC RING, AND PROCESS FOR PRODUCING THE SAME | RCC1, AFF4, TPR | CES2 2373/4885ALDH1A1 3317/4885CYP3A4 1482/4885 |
| US-20020099039-A1 | Vitamin D3 derivative and treating agent for inflammatory respiratory disease using same | CYP24A1, VDR, CYP2R1 | CES2 4844/4885ALDH1A1 800/4885CYP3A4 944/4885 |
| US-20020091109-A1 | Vitamin D3 derivative and treating agent for inflammatory respiratory disease using same | CYP24A1, VDR, CYP2R1 | CES2 4844/4885ALDH1A1 800/4885CYP3A4 944/4885 |
| US-20120028961-A1 | 6 Substituted 2, 3,4,5 Tetrahydro-1H-Benzo[d]Azepines as 5-HT2c Receptor Agonist | HTR2C, HTR4, HTR1A | CES2 958/4885ALDH1A1 500/4885CYP3A4 361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.