Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.41 |
| ▸ | HTR3B | O95264 | 3/20 | 0.41 |
| ▸ | HTR2C | P28335 | 3/20 | 0.41 |
| ▸ | HTR3A | P46098 | 3/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | SMO | Q99835 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6586750 | 0.79 | SIGMAR1 (0.58) | ALDH1A1KDM4EKMT2A | |
| SCHEMBL6587595 | 0.76 | HTR1A (0.51) | HTR1AALDH1A1MAPTALOX15TSHR | |
| SCHEMBL6586359 | 0.76 | HTR1A (0.58) | HTR1AALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL4555805 | 0.75 | MAPT (0.48) | HTR1AALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL4555931 | 0.72 | ALDH1A1 (0.42) | HTR1AALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL6587599 | 0.71 | KMT2A (0.60) | HTR1AALDH1A1MAPTTSHRMEN1 | |
| SCHEMBL27793480 | 0.70 | MC4R (0.59) | HRH4NPC1RAB9A | |
| SCHEMBL11127227 | 0.70 | SIGMAR1 (0.53) | DRD4DRD2DRD3 | |
| SCHEMBL4555285 | 0.68 | PLD1 (0.49) | ALDH1A1LMNAKDM4EMAPTHPGD | |
| SCHEMBL8708628 | 0.67 | POLB (0.53) | ALDH1A1LMNAKDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161424-B1 | NEW DIAZOLE DERIVATIVES AS SEROTONERGIC AGENTS | WYETH CORP (US) | 2004-06-02 | — | — | EP | claimed |