Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.67 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 5/20 | 0.37 |
| ▸ | CTSL | P07711 | 4/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.35 |
| ▸ | GPR6 | P46095 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27489107 | 0.80 | HTR1A (1.00) | HTR1ADRD4DRD3CTSSCTSL | |
| SCHEMBL6590854 | 0.80 | HTR1A (1.00) | HTR1ADRD4DRD3CTSSCTSL | |
| SCHEMBL6586359 | 0.72 | HTR1A (0.58) | HTR1ADRD4DRD3AKT1 | |
| Fumaric Acid SCHEMBL6592709 | 0.71 | HTR1A (0.58) | HTR1AAKT1 | |
| SCHEMBL6589346 | 0.69 | HTR1A (0.58) | HTR1AAKT1 | |
| SCHEMBL272157 | 0.67 | ATM (0.64) | CTSSCTSLAKT1 | |
| SCHEMBL6586642 | 0.67 | HTR1A (0.55) | HTR1AAKT1 | |
| SCHEMBL13244198 | 0.66 | ATM (0.59) | CTSSCTSL | |
| SCHEMBL6586750 | 0.66 | SIGMAR1 (0.58) | — | |
| SCHEMBL6586733 | 0.66 | HTR1A (0.61) | HTR1ADRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161424-B1 | NEW DIAZOLE DERIVATIVES AS SEROTONERGIC AGENTS | WYETH CORP (US) | 2004-06-02 | — | — | EP | claimed |