Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6589548 | 0.88 | HTR1A (0.74) | HTR1AALDH1A1TSHRLMNAALOX15 | |
| SCHEMBL6588749 | 0.84 | HTR1A (1.00) | HTR1AALDH1A1TSHRLMNAALOX15 | |
| SCHEMBL6588614 | 0.75 | HTR1A (0.66) | HTR1AALDH1A1TSHRLMNAALOX15 | |
| SCHEMBL6586728 | 0.75 | HTR1A (0.66) | HTR1AALDH1A1TSHRLMNAALOX15 | |
| SCHEMBL6588617 | 0.72 | HTR1A (0.61) | HTR1AALDH1A1TSHRLMNAALOX15 | |
| SCHEMBL6586733 | 0.72 | HTR1A (0.61) | HTR1AALDH1A1TSHRLMNAALOX15 | |
| SCHEMBL6586789 | 0.64 | HTR1A (0.61) | HTR1AALDH1A1TSHRALOX15HSD17B10 | |
| Hydrochloric Acid SCHEMBL4728303 | 0.62 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10MAPK1KMT2A | |
| SCHEMBL7398030 | 0.61 | MMP8 (0.53) | ALDH1A1LMNAHSD17B10KMT2APOLB | |
| SCHEMBL17244724 | 0.61 | ALDH1A1 (1.00) | HTR1AALDH1A1TSHRLMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161424-B1 | NEW DIAZOLE DERIVATIVES AS SEROTONERGIC AGENTS | WYETH CORP (US) | 2004-06-02 | — | — | EP | claimed |