SCHEMBL6597539

SCHEMBL6597539

CC(C)[n+]1cccc(-c2cc(Cc3ccccc3)n[nH]2)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.36
POLB P06746 2/20 0.36
ALDH1A1 P00352 2/20 0.35
NR1H2 P55055 1/20 0.35
NR1H3 Q13133 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
HPGD P15428 1/20 0.34
TSHR P16473 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
GPR84 Q9NQS5 1/20 0.34
DRD4 P21917 1/20 0.33
DRD3 P35462 1/20 0.33
NPC1 O15118 1/20 0.32
JAK2 O60674 2/20 0.32
ROCK2 O75116 2/20 0.32
PRKACA P17612 2/20 0.32
CDK2 P24941 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL1194124 0.99 RAB9A (0.35) RAB9APOLBALDH1A1NR1H2NR1H3
SCHEMBL6599975 0.81 CYP1A2 (0.54) RAB9APOLBALDH1A1NR1H2NR1H3
SCHEMBL28114539 0.80 RAB9A (0.53) RAB9APOLBALDH1A1NR1H2NR1H3
Hydrochloric Acid SCHEMBL1194183 0.80 LMNA (0.56) RAB9APOLBALDH1A1NR1H2NR1H3
SCHEMBL6596014 0.75 KMT2A (0.47) RAB9AALDH1A1SMN1; SMN2CYP1A2CYP2D6
Bromide SCHEMBL1193597 0.74 KMT2A (0.49) RAB9AALDH1A1SMN1; SMN2CYP1A2CYP2D6
SCHEMBL6597674 0.71 HPGDS (0.53) ALDH1A1SMN1; SMN2CYP1A2CYP2D6HPGDS
SCHEMBL20239625 0.71 NR1H2 (0.49) RAB9AALDH1A1NR1H2NR1H3SMN1; SMN2
SCHEMBL27768226 0.71 PTGS2 (0.44) RAB9APOLB
Hydrochloric Acid SCHEMBL7070348 0.71 HSP90AA1 (0.44) ALDH1A1GSK3BGSK3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1373263-B1 HETEROCYCLIC COMPOUNDS FOR AGING-RELATED AND DIABETIC VASCULAR COMPLICATIONS TORRENT PHARMACEUTICALS LTD (IN) 2004-10-27 EP claimed