Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 3/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 2/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.34 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.34 |
| ▸ | GAK | O14976 | 4/20 | 0.33 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.33 |
| ▸ | COQ8A | Q8NI60 | 2/20 | 0.33 |
| ▸ | NLK | Q9UBE8 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24715778 | 0.76 | NQO2 (0.39) | NQO2DYRK1ANSD2CASP6G6PD | |
| SCHEMBL7188128 | 0.75 | ALDH1A1 (0.42) | NQO2DYRK1AG6PDALDH1A1CYP1A2 | |
| SCHEMBL25130366 | 0.72 | ALOX5AP (0.39) | NQO2DYRK1ANSD2CASP6G6PD | |
| SCHEMBL7213113 | 0.70 | CA2 (0.50) | CYP3A4MAPTCA2CA4TUBB4A | |
| SCHEMBL24715844 | 0.70 | SLC6A3 (0.39) | NQO2DYRK1AG6PDALDH1A1CYP1A2 | |
| SCHEMBL20292984 | 0.69 | NSD2 (0.40) | NQO2DYRK1ANSD2CASP6G6PD | |
| SCHEMBL7186122 | 0.68 | MAPT (0.44) | NQO2NSD2CASP6APAF1TDP2 | |
| SCHEMBL31436390 | 0.68 | KDM4E (0.45) | G6PDGAKALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL1556931 | 0.68 | KDM4E (0.45) | G6PDGAKALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL24715893 | 0.68 | G6PD (0.60) | NQO2DYRK1ANSD2CASP6G6PD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1080090-B1 | ANTITUMOUR 1,5-DIAZAANTHRAQUINONES | UNIV MADRID COMPLUTENSE (ES) | 2004-02-25 | — | — | EP | disclosed |
| US-6525063-B2 | 3,7-dimethyl-1,5-diazaanthraquinone for example | UNIVERSIDAD COMPLUTENSE DE MADRID (ES) | 2003-02-25 | — | — | US | disclosed |
| US-20020099066-A1 | Antitumour 1,5-diazaanthraquinones | UNIVERSIDAD COMPLUTENSE DE MADRID (ES) | 2002-07-25 | — | — | US | disclosed |
| EP-1080090-A1 | ANTITUMOUR 1,5-DIAZAANTHRAQUINONES | UNIVERSIDAD COMPLUTENSE DE MADRID (ES) | 2001-03-07 | — | — | EP | disclosed |
| WO-1999059996-A1 | ANTITUMOUR 1,5-DIAZAANTHRAQUINONES | UNIVERSIDAD COMPLUTENSE DE MADRID (ES) | 1999-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099066-A1 | Antitumour 1,5-diazaanthraquinones | PRMT7, TPD52L2, DRD4 | NQO2 70/4885DYRK1A 2463/4885NSD2 103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.