SCHEMBL6599706

SCHEMBL6599706

N#C/C(=C\c1ccc(O)c(O)c1)C(=O)NCCCc1cccc(O)c1

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 16/20 0.82
KDM4E B2RXH2 5/20 0.82
MEN1 O00255 5/20 0.82
ALDH1A1 P00352 5/20 0.82
CYP3A4 P08684 5/20 0.82
MAPT P10636 5/20 0.82
HPGD P15428 5/20 0.82
ALOX15 P16050 5/20 0.82
ALOX12 P18054 5/20 0.82
MAPK1 P28482 5/20 0.82
RECQL P46063 5/20 0.82
BLM P54132 5/20 0.82
KMT2A Q03164 5/20 0.82
HSD17B10 Q99714 5/20 0.82
TDP1 Q9NUW8 5/20 0.82
CYP1A2 P05177 4/20 0.82
TP53 P04637 4/20 0.82
NFKB1 P19838 4/20 0.82
PMP22 Q01453 4/20 0.82
SMN1; SMN2 Q16637 4/20 0.82

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6599711 1.00 EGFR (0.82) EGFRKDM4EMEN1ALDH1A1CYP3A4
SCHEMBL30274781 1.00 EGFR (0.82) EGFRKDM4EMEN1ALDH1A1CYP3A4
SCHEMBL645291 0.90 EGFR (1.00) EGFRKDM4EMEN1ALDH1A1CYP3A4
SCHEMBL29378814 0.90 EGFR (1.00) EGFRKDM4EMEN1ALDH1A1CYP3A4
SCHEMBL645290 0.90 EGFR (1.00) EGFRKDM4EMEN1ALDH1A1CYP3A4
SCHEMBL21277338 0.89 EGFR (0.84) EGFRKDM4EMEN1ALDH1A1CYP3A4
SCHEMBL2533402 0.87 EGFR (1.00) EGFRKDM4EMEN1ALDH1A1CYP3A4
SCHEMBL6055311 0.87 EGFR (1.00) EGFRKDM4EMEN1ALDH1A1CYP3A4
SCHEMBL29376415 0.87 EGFR (1.00) EGFRKDM4EMEN1ALDH1A1CYP3A4
SCHEMBL3486952 0.87 EGFR (1.00) EGFRKDM4EMEN1ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144882-A1 ANTI-NECTIN-4 ANTIBODY DRUG CONJUGATE AND USE THEREOF BIO-THERA SOLUTIONS, LTD. (CN) 2026-05-28 US claimed
US-20260008848-A1 ANTI-NECTIN-4 ANTIBODY, AND ANTIBODY-DRUG CONJUGATE AND USE THEREOF BIO THERA SOLUTIONS LTD (CN) 2026-01-08 US claimed
US-20250381283-A1 METHOD FOR TREATING SOLID TUMOR BIO THERA SOLUTIONS LTD (CN) 2025-12-18 US claimed
US-20250333498-A1 ANTI-CLDN18.2 ANTIBODY, AND ANTIBODY-DRUG CONJUGATE AND USE THEREOF BIO THERA SOLUTIONS LTD (CN) 2025-10-30 US claimed
US-20250262316-A1 ANTIBODY-DRUG CONJUGATE AND APPLICATION THEREOF BIO-THERA SOLUTIONS, LTD. (CN) 2025-08-21 US claimed
US-20250249114-A1 METHOD FOR TREATING HER2-POSITIVE SOLID TUMOR BIO-THERA SOLUTIONS, LTD. (CN) 2025-08-07 US claimed
EP-4556027-A1 ANTI-NECTIN-4 ANTIBODY DRUG CONJUGATE AND USE THEREOF Bio-Thera Solutions, Ltd. (CN) 2025-05-21 EP claimed
EP-4545099-A1 METHOD FOR TREATING SOLID TUMOR Bio-Thera Solutions, Ltd. (CN) 2025-04-30 EP claimed
EP-4538291-A1 ANTI-NECTIN-4 ANTIBODY, AND ANTIBODY-DRUG CONJUGATE AND USE THEREOF Bio-Thera Solutions, Ltd. (CN) 2025-04-16 EP claimed
EP-4534105-A1 ANTI-CLDN18.2 ANTIBODY, AND ANTIBODY-DRUG CONJUGATE AND USE THEREOF Bio-Thera Solutions, Ltd. (CN) 2025-04-09 EP claimed
US-20250059274-A1 ANTI-FRa ANTIBODY, AND ANTIBODY-DRUG CONJUGATE AND USE THEREOF BIO-THERA SOLUTIONS, LTD. (CN) 2025-02-20 US claimed
EP-4509141-A1 METHOD FOR TREATING HER2-POSITIVE SOLID TUMOR Bio-Thera Solutions, Ltd. (CN) 2025-02-19 EP claimed
EP-4455164-A1 ANTI-FRalpha ANTIBODY, AND ANTIBODY-DRUG CONJUGATE AND USE THEREOF Bio-Thera Solutions, Ltd. (CN) 2024-10-30 EP claimed
US-20240269315-A1 DRUG CONJUGATE AND USE THEREOF BIO-THERA SOLUTIONS, LTD. (CN) 2024-08-15 US claimed
EP-4349371-A1 DRUG CONJUGATE AND USE THEREOF Bio-Thera Solutions, Ltd. (CN) 2024-04-10 EP claimed
WO-2023232080-A1 ANTI-CLDN18.2 ANTIBODY, AND ANTIBODY-DRUG CONJUGATE AND USE THEREOF 百奥泰生物制药股份有限公司 2023-12-07 WO claimed
WO-2023116911-A1 ANTI-FRα ANTIBODY, AND ANTIBODY-DRUG CONJUGATE AND USE THEREOF 百奥泰生物制药股份有限公司 2023-06-29 WO claimed
EP-1414526-A2 ANTIANGIOGENIC COMBINATION THERAPY FOR THE TREATMENT OF CANCER Pharmacia Corporation (US) 2004-05-06 EP claimed
WO-2002085459-A2 ANTIANGIOGENIC COMBINATION THERAPY FOR THE TREATMENT OF CANCER PHARMACIA CORPORATION (US) 2002-10-31 WO claimed
US-20020103141-A1 Antiangiogenic combination therapy for the treatment of cancer PHARMACIA CORPORATION 2002-08-01 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008848-A1 ANTI-NECTIN-4 ANTIBODY, AND ANTIBODY-DRUG CONJUGATE AND USE THEREOF NECTIN4, VSIG8, IGSF11 EGFR 1917/4885KDM4E 1440/4885MEN1 1693/4885
US-20250249114-A1 METHOD FOR TREATING HER2-POSITIVE SOLID TUMOR ERBB2, EGFR, ERBB3 EGFR 2/4885KDM4E 3617/4885MEN1 2613/4885
US-20260144882-A1 ANTI-NECTIN-4 ANTIBODY DRUG CONJUGATE AND USE THEREOF NECTIN4, CD22, NGFR EGFR 467/4885KDM4E 4366/4885MEN1 1105/4885
US-20020103141-A1 Antiangiogenic combination therapy for the treatment of cancer TOP2A, TOP2B, TOP1 EGFR 2486/4885KDM4E 2489/4885MEN1 3673/4885
US-20250333498-A1 ANTI-CLDN18.2 ANTIBODY, AND ANTIBODY-DRUG CONJUGATE AND USE THEREOF CNTN1, EPCAM, SLC22A8 EGFR 1984/4885KDM4E 2741/4885MEN1 2360/4885
US-20240269315-A1 DRUG CONJUGATE AND USE THEREOF CD47, SLC10A1, SSB EGFR 147/4885KDM4E 1362/4885MEN1 326/4885
US-20250381283-A1 METHOD FOR TREATING SOLID TUMOR TPM4, TPM3, TPST2 EGFR 250/4885KDM4E 4103/4885MEN1 2103/4885
US-20250059274-A1 ANTI-FRa ANTIBODY, AND ANTIBODY-DRUG CONJUGATE AND USE THEREOF FOLR1, FOLR2, DHFR EGFR 117/4885KDM4E 4761/4885MEN1 4451/4885
US-20250262316-A1 ANTIBODY-DRUG CONJUGATE AND APPLICATION THEREOF FCGR2A, FCGR1A, FCGR3B EGFR 49/4885KDM4E 2333/4885MEN1 1874/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.