Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 5/20 | 0.55 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.55 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | STK17B | O94768 | 1/20 | 0.52 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.52 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.52 |
| ▸ | PDE2A | O00408 | 1/20 | 0.51 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.51 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.51 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.49 |
| ▸ | WNT3A | P56704 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29843483 | 1.00 | ROCK2 (0.55) | ROCK2ROCK1PTPN7MEN1KMT2A | |
| SCHEMBL19555316 | 0.88 | PTPN7 (0.55) | ROCK2ROCK1PTPN7MEN1KMT2A | |
| SCHEMBL30025182 | 0.88 | PTPN7 (0.55) | ROCK2ROCK1PTPN7MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL20974298 | 0.81 | PTPN7 (0.48) | ROCK2ROCK1PTPN7MEN1KMT2A | |
| SCHEMBL19555379 | 0.81 | MEN1 (0.51) | ROCK2ROCK1MEN1KMT2APOLB | |
| SCHEMBL6574033 | 0.80 | RAB9A (0.49) | ROCK2ROCK1MEN1KMT2APOLB | |
| SCHEMBL5410655 | 0.78 | ROCK2 (0.50) | ROCK2ROCK1MEN1KMT2APDE3B | |
| SCHEMBL4076964 | 0.78 | PTPN7 (0.85) | PTPN7MEN1KMT2APDE2APDE3B | |
| SCHEMBL5019916 | 0.78 | ESR1 (0.66) | — | |
| SCHEMBL15226600 | 0.78 | ESR1 (0.66) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230150929-A1 | SELECTIVE NON-CYCLIC NUCLEOTIDE ACTIVATORS FOR THE CAMP SENSOR EPAC1 | UNIV TEXAS (US) | 2023-05-18 | — | — | US | disclosed |
| CN-116134015-A | Selective acyclic nucleotide activating factor for CAMP sensor EPAC1 | 得克萨斯州大学系统董事会 | 2023-05-16 | — | — | CN | disclosed |
| EP-1403255-A1 | Rho KINASE INHIBITORS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2004-03-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150929-A1 | SELECTIVE NON-CYCLIC NUCLEOTIDE ACTIVATORS FOR THE CAMP SENSOR EPAC1 | CREB1, RAPGEF4, ATF4 | ROCK2 1434/4885ROCK1 1730/4885PTPN7 1664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.