Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | YAP1 | P46937 | 3/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6600523 | 0.88 | ALDH1A1 (0.43) | KMT2AMEN1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL6600370 | 0.87 | CTSS (0.47) | KMT2AMEN1ALDH1A1POLBCTSB | |
| SCHEMBL6600519 | 0.86 | YAP1 (0.46) | MAPK1KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL6162914 | 0.77 | MAPK1 (0.62) | MAPK1KMT2AMEN1YAP1CACNA1B | |
| SCHEMBL6162909 | 0.77 | MAPK1 (0.62) | MAPK1KMT2AMEN1YAP1CACNA1B | |
| SCHEMBL8933253 | 0.72 | TACR1 (0.45) | KMT2AMEN1ALDH1A1POLBCAPN1 | |
| SCHEMBL6600601 | 0.72 | GHSR (0.51) | KMT2AMEN1ALDH1A1POLBCTSB | |
| SCHEMBL6600255 | 0.72 | YAP1 (0.45) | MAPK1KMT2AMEN1ALDH1A1YAP1 | |
| SCHEMBL6600367 | 0.71 | CTSS (0.56) | ALDH1A1CTSB | |
| SCHEMBL6601229 | 0.71 | KMT2A (0.45) | MAPK1KMT2AMEN1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996022997-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1996-08-01 | — | — | WO | disclosed |