SCHEMBL661377

SCHEMBL661377

COCCOCCOCCOCCOCCOCCOS(C)(=O)=O

nearest known ligand 0.52

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
USP2 O75604 2/20 0.52
TSHR P16473 2/20 0.52
KDM4E B2RXH2 1/20 0.52
ALDH1A1 P00352 1/20 0.52
LMNA P02545 1/20 0.52
MMP9 P14780 1/20 0.52
ALOX15 P16050 1/20 0.52
CA2 P00918 1/20 0.45
MLKL Q8NB16 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL875176 1.00 USP2 (0.52) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL29870420 1.00 USP2 (0.52) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL26299278 1.00 USP2 (0.52) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL661478 1.00 USP2 (0.52) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL661021 1.00 USP2 (0.52) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL851826 1.00 USP2 (0.52) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL101673 1.00 USP2 (0.52) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL6555279 1.00 USP2 (0.52) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL660625 1.00 USP2 (0.52) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL16559904 1.00 USP2 (0.52) USP2TSHRKDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3814356-B1 TRIAZOLOTRIAZINE DERIVATIVES AS A2A RECEPTOR ANTAGONISTS ZHEJIANG VIMGREEN PHARMACEUTICALS LTD (CN) 2026-03-11 EP disclosed
US-11845751-B2 Triazolotriazine derivatives as A2A receptor antagonists ZHEJIANG VIMGREEN PHARMACEUTICALS, LTD. (CN) 2023-12-19 US disclosed
EP-3406614-B1 OPIOID RECEPTOR ANTAGONIST CONJUGATE AND USE THEREOF SHANGHAI HANMAI BIO PHARMA CO LTD (CN) 2022-12-28 EP disclosed
US-11311533-B2 Opioid receptor antagonist conjugate and use thereof Shanghai Hanmai Bio-Pharma Co., Ltd. (CN) 2022-04-26 US disclosed
US-20210332055-A1 TRIAZOLOTRIAZINE DERIVATIVES AS A2A RECEPTOR ANTAGONISTS ZHEJIANG VIMGREEN PHARMACEUTICALS, LTD. (CN) 2021-10-28 US disclosed
US-10596268-B2 Conjugate of dezocine and polyethylene glycol JENKEM TECHNOLOGY CO., LTD. (BEIJING) (CN) 2020-03-24 US disclosed
US-20190298845-A1 CONJUGATE OF DEZOCINE AND POLYETHYLENE GLYCOL JENKEM TECHNOLOGY CO., LTD. (BEIJING) (CN) 2019-10-03 US disclosed
US-8551220-B2 Sulfur dioxide absorbent comprising ionic liquid KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2013-10-08 US disclosed
US-20120042778-A1 SULFUR DIOXIDE ABSORBENT COMPRISING IONIC LIQUID KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2012-02-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10596268-B2 Conjugate of dezocine and polyethylene glycol OPRM1, DAO, DDO USP2 560/4885TSHR 3924/4885KDM4E 1342/4885
US-20120042778-A1 SULFUR DIOXIDE ABSORBENT COMPRISING IONIC LIQUID TST, CBS, ARSA USP2 1241/4885TSHR 1824/4885KDM4E 1504/4885
US-20190298845-A1 CONJUGATE OF DEZOCINE AND POLYETHYLENE GLYCOL OPRM1, DAO, DDO USP2 560/4885TSHR 3924/4885KDM4E 1342/4885
US-11845751-B2 Triazolotriazine derivatives as A2A receptor antagonists ADORA2A, ADORA1, ADORA3 USP2 3328/4885TSHR 63/4885KDM4E 3952/4885
US-11311533-B2 Opioid receptor antagonist conjugate and use thereof OPRL1, OPRM1, OGFR USP2 2647/4885TSHR 347/4885KDM4E 2838/4885
US-20210332055-A1 TRIAZOLOTRIAZINE DERIVATIVES AS A2A RECEPTOR ANTAGONISTS ADORA2A, ADORA1, ADORA3 USP2 3328/4885TSHR 63/4885KDM4E 3952/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.