SCHEMBL660625

SCHEMBL660625

COCCOCCOCCOS(C)(=O)=O

nearest known ligand 0.52

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
USP2 O75604 2/20 0.52
TSHR P16473 2/20 0.52
KDM4E B2RXH2 1/20 0.52
ALDH1A1 P00352 1/20 0.52
LMNA P02545 1/20 0.52
MMP9 P14780 1/20 0.52
ALOX15 P16050 1/20 0.52
CA2 P00918 1/20 0.45
MLKL Q8NB16 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL875176 1.00 USP2 (0.52) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL29870420 1.00 USP2 (0.52) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL26299278 1.00 USP2 (0.52) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL661478 1.00 USP2 (0.52) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL661021 1.00 USP2 (0.52) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL851826 1.00 USP2 (0.52) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL661377 1.00 USP2 (0.52) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL101673 1.00 USP2 (0.52) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL6555279 1.00 USP2 (0.52) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL16559904 1.00 USP2 (0.52) USP2TSHRKDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3814356-B1 TRIAZOLOTRIAZINE DERIVATIVES AS A2A RECEPTOR ANTAGONISTS ZHEJIANG VIMGREEN PHARMACEUTICALS LTD (CN) 2026-03-11 EP disclosed
US-20250313572-A1 MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE ABBVIE INC (US) 2025-10-09 US disclosed
EP-4612196-A1 GRAFTABLE BIOCIDAL LINKERS AND POLYMERS AND USES THEREOF Debogy Molecular, Inc. (US) 2025-09-10 EP disclosed
US-20250214954-A1 METHODS OF TREATING HIV USING TRITERPENE DERIVATIVES HETERO LABS LIMITED (IN) 2025-07-03 US disclosed
US-12275712-B2 Triterpene derivatives as HIV inhibitors HETERO LABS LIMITED (IN) 2025-04-15 US disclosed
EP-4504694-A1 IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES Capstan Therapeutics, Inc. (US) 2025-02-12 EP disclosed
EP-3824325-B1 VEHICLE SENSORS COMPRISING REPELLENT SURFACE, PROTECTIVE FILMS, REPELLENT COATING COMPOSITIONS, AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2025-01-08 EP disclosed
US-20240299311-A1 IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES CAPSTAN THERAPEUTICS, INC. (US) 2024-09-12 US disclosed
US-20240228509-A1 MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE ABBVIE INC (US) 2024-07-11 US disclosed
US-12023661-B2 Nitrogen heterocyclic carbene ligands and ruthenium catalysts thereof, preparation method therefor and application thereof Paimai New Materials (chengdu) Co., Ltd. (CN) 2024-07-02 US disclosed
US-20030027748-A1 Mixtures of insulin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same BIOCON LIMITED (IN) 2003-02-06 US disclosed
US-20030027995-A1 Mixtures of growth hormone drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same BIOCON LIMITED (IN) 2003-02-06 US disclosed
WO-2002098446-A1 MIXTURES OF DRUG-OLIGOMER CONJUGATES COMPRISING POLYALKYLENE GLYCOL, USES THEREOF, AND METHODS OF MAKING SAME NOBEX CORPORATION (US) 2002-12-12 WO disclosed
WO-2002098452-A1 MIXTURES OF GROWTH HORMONE DRUG-OLIGOMER CONJUGATES COMPROMISING POLYALKYLENE GLYCOL, USES THEREOF, AND METHODS OF MAKING SAME NOBEX CORPORATION (US) 2002-12-12 WO disclosed
WO-2001034573-A1 COMPOUNDS ASTRAZENECA AB (SE) 2001-05-17 WO disclosed
US-5492687-A X-RAY CONTRAST AGENTS STERLING WINTHROP INC. (US) 1996-02-20 US disclosed
US-5466435-A X-ray contrast agents, radiology STERLING WINTHROP INC. (US) 1995-11-14 US disclosed
EP-0619121-A2 Compositions of iodophenoxy alkylene ethers for visualization of the gastrointestinal tract NYCOMED IMAGING AS (NO) 1994-10-12 EP disclosed
US-5348727-A Diagnostics STERLING WINTHROP INC. (US) 1994-09-20 US disclosed
EP-0614670-A2 Compositions of iodophenoxy alkylene ethers in film-formin materials for visualization of the gastrointestinal tract NYCOMED IMAGING AS (NO) 1994-09-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240228509-A1 MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE MCL1, BCL2A1, BCL2L10 USP2 2815/4885TSHR 1846/4885KDM4E 1725/4885
US-20030027748-A1 Mixtures of insulin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same IAPP, SI, IDE USP2 2083/4885TSHR 1412/4885KDM4E 4615/4885
US-20250313572-A1 MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE MCL1, BCL2A1, BCL2L10 USP2 2815/4885TSHR 1846/4885KDM4E 1725/4885
US-12275712-B2 Triterpene derivatives as HIV inhibitors CCR5, CYP51A1, CYP4A11 USP2 4552/4885TSHR 3231/4885KDM4E 1058/4885
US-20240299311-A1 IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES PLTP, LNPEP, PLIN3 USP2 4861/4885TSHR 894/4885KDM4E 4434/4885
US-20030027995-A1 Mixtures of growth hormone drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same GHRHR, GHSR, GHITM USP2 774/4885TSHR 43/4885KDM4E 4494/4885
US-20250214954-A1 METHODS OF TREATING HIV USING TRITERPENE DERIVATIVES CCR5, HSD17B7, CYP51A1 USP2 4605/4885TSHR 3125/4885KDM4E 1708/4885
US-12023661-B2 Nitrogen heterocyclic carbene ligands and ruthenium catalysts thereof, preparation method therefor and application thereof WEE2, WEE1, FARSB USP2 3586/4885TSHR 4011/4885KDM4E 4474/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.