SCHEMBL101673

SCHEMBL101673

COCCOCCOS(C)(=O)=O

nearest known ligand 0.52

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
USP2 O75604 2/20 0.52
TSHR P16473 2/20 0.52
KDM4E B2RXH2 1/20 0.52
ALDH1A1 P00352 1/20 0.52
LMNA P02545 1/20 0.52
MMP9 P14780 1/20 0.52
ALOX15 P16050 1/20 0.52
CA2 P00918 1/20 0.45
MLKL Q8NB16 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL875176 1.00 USP2 (0.52) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL29870420 1.00 USP2 (0.52) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL26299278 1.00 USP2 (0.52) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL661478 1.00 USP2 (0.52) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL661021 1.00 USP2 (0.52) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL851826 1.00 USP2 (0.52) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL661377 1.00 USP2 (0.52) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL6555279 1.00 USP2 (0.52) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL660625 1.00 USP2 (0.52) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL16559904 1.00 USP2 (0.52) USP2TSHRKDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111589420-A Millimeter-grade macroporous-mesoporous carbon sphere/cup [4] -double crown-6 interpenetrating composite material and preparation method and application thereof 东华理工大学 2020-08-28 CN claimed
CN-110180504-A Carbon-based asymmetric double crown supermolecule hybrid material of one kind and its preparation method and application 东华理工大学 2019-08-30 CN claimed
US-20250034143-A1 SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF HYDRA BIOSCIENCES, LLC (US) 2025-01-30 US disclosed
US-12024486-B2 Lipocationic dendrimers and uses thereof THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2024-07-02 US disclosed
US-11958854-B2 Substituted xanthines and methods of use thereof HYDRA BIOSCIENCES, LLC (US) 2024-04-16 US disclosed
US-20240025848-A1 LIPOCATIONIC DENDRIMERS AND USES THEREOF THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2024-01-25 US disclosed
US-11858884-B2 Compositions and methods for modulating gene or gene product in cells THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2024-01-02 US disclosed
US-20230320995-A1 IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES CAPSTAN THERAPEUTICS, INC. (US) 2023-10-12 US disclosed
US-11660303-B2 2-phenylimidazo[4,5-b]pyridin-7-amine derivates useful as inhibitors of mammalian tyrosine kinase ROR1 activity KANCERA AB (SE) 2023-05-30 US disclosed
EP-3294714-B1 MORPHINAN DERIVATIVES FOR THE TREATMENT OF NEUROPATHIC PAIN NEKTAR THERAPEUTICS (US) 2023-03-15 EP disclosed
US-20230040259-A1 SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF HYDRA BIOSCIENCES, LLC (US) 2023-02-09 US disclosed
WO-2009026537-A1 BENZYLBENZENE DERIVATIVES AND METHODS OF USE THERACOS, INC. (US) 2009-02-26 WO disclosed
US-20070135351-A1 Neuropeptide-2 receptor (Y-2R) agonists and uses thereof CONDE-KNAPE KARIN 2007-06-14 US disclosed
WO-2005000941-A1 NOVEL POLYMER COMPOSITIONS DOW GLOBAL TECHNOLOGIES, INC. (US) 2005-01-06 WO disclosed
US-20040249067-A1 Novel polymer compositions FOX MARTIN EDWARD (GB) 2004-12-09 US disclosed
US-20040249119-A1 Novel mPEG propionaldehyde precursor FOX MARTIN EDWARD (GB) 2004-12-09 US disclosed
EP-0349748-B1 SUBSTITUTED N-ARYL-NITROGEN CONTAINING HETEROCYCLES BAYER AG (DE) 1992-11-19 EP disclosed
US-5118849-A Arylamines intermediates BAYER AKTIENGESELLSCHAFT (DE) 1992-06-02 US disclosed
US-5039334-A Herbicidal and plant growth-regulating substituted N-aryl nitrogen heterocycles BAYER AKTIENGESELLSCHAFT (DE) 1991-08-13 US disclosed
EP-0349748-A1 Substituted N-aryl-nitrogen containing heterocycles BAYER AG (DE) 1990-01-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135351-A1 Neuropeptide-2 receptor (Y-2R) agonists and uses thereof NPY2R, NPY1R, NPY4R USP2 2739/4885TSHR 81/4885KDM4E 3805/4885
US-20240025848-A1 LIPOCATIONIC DENDRIMERS AND USES THEREOF LIPA, LIPC, TLR9 USP2 3570/4885TSHR 3143/4885KDM4E 4836/4885
US-12024486-B2 Lipocationic dendrimers and uses thereof LIPA, LIPC, TLR9 USP2 3570/4885TSHR 3143/4885KDM4E 4836/4885
US-20230320995-A1 IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES PLTP, LNPEP, PLIN3 USP2 4861/4885TSHR 894/4885KDM4E 4434/4885
US-11958854-B2 Substituted xanthines and methods of use thereof TRPC5, TRPC7, TRPC4 USP2 4322/4885TSHR 4540/4885KDM4E 3549/4885
US-20230040259-A1 SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF TRPC5, TRPC7, TRPC4 USP2 4322/4885TSHR 4540/4885KDM4E 3549/4885
US-20250034143-A1 SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF TRPC5, TRPC7, TRPC4 USP2 4322/4885TSHR 4540/4885KDM4E 3549/4885
US-11858884-B2 Compositions and methods for modulating gene or gene product in cells DGKB, DGKG, DGKA USP2 2976/4885TSHR 4629/4885KDM4E 4699/4885
US-11660303-B2 2-phenylimidazo[4,5-b]pyridin-7-amine derivates useful as inhibitors of mammalian tyrosine kinase ROR1 activity ROR1, RORB, RORA USP2 4095/4885TSHR 1024/4885KDM4E 2579/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.