Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.42 |
| ▸ | WNT3A | P56704 | 3/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6874059 | 0.87 | MAOA (0.50) | TAS1R3TAS1R1TUBB4ATUBBTUBA3C | |
| SCHEMBL1675118 | 0.77 | CA12 (0.53) | TAS1R3TAS1R1TUBB4ATUBBTUBA3C | |
| SCHEMBL6874334 | 0.77 | TAS1R3 (0.45) | TAS1R3TAS1R1TUBB4ATUBBTUBA3C | |
| SCHEMBL6865989 | 0.76 | ACHE (0.41) | TAS1R3TAS1R1TUBB4ATUBBTUBA3C | |
| SCHEMBL27752787 | 0.75 | TAS1R3 (0.50) | TAS1R3TAS1R1TUBB4ATUBBTUBA3C | |
| SCHEMBL8132038 | 0.74 | TAS1R3 (0.57) | TAS1R3TAS1R1TUBB4ATUBBTUBA3C | |
| SCHEMBL29377304 | 0.73 | TUBB4A (0.58) | TAS1R3TAS1R1TUBB4ATUBBTUBA3C | |
| SCHEMBL103794 | 0.73 | TUBB4A (0.58) | TAS1R3TAS1R1TUBB4ATUBBTUBA3C | |
| SCHEMBL31094660 | 0.72 | MAOA (0.67) | TAS1R3TAS1R1TUBB4ATUBBTUBA3C | |
| SCHEMBL1222893 | 0.72 | MAOA (0.67) | TAS1R3TAS1R1TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1479677-A1 | New indole derivatives as factor xa inhibitors | Aventis Pharma Deutschland GmbH (DE) | 2004-11-24 | — | — | EP | disclosed |