Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5242857 | 0.87 | ALDH1A1 (0.53) | SIGMAR1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL1332850 | 0.80 | CHRM3 (0.56) | SIGMAR1MEN1KMT2ACHRM3 | |
| SCHEMBL6624933 | 0.77 | DRD2 (0.56) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL5183896 | 0.77 | LDHA (0.52) | SIGMAR1ALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL6140255 | 0.77 | VEGFA (0.53) | ALDH1A1MEN1TSHRKMT2ACHRM2 | |
| SCHEMBL2730746 | 0.76 | KCNH2 (0.71) | KCNH2 | |
| SCHEMBL22800973 | 0.76 | KMT2A (0.47) | ALDH1A1MEN1KMT2ACHRM2CHRM4 | |
| SCHEMBL6620732 | 0.75 | KMT2A (0.50) | ALDH1A1MEN1TSHRKMT2APOLB | |
| SCHEMBL5815688 | 0.75 | KDM4E (0.55) | SIGMAR1ALDH1A1CHRM2CHRM4CHRM1 | |
| SCHEMBL3712707 | 0.74 | MEN1 (0.59) | SIGMAR1MEN1KMT2ACHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389189-A2 | MELANIN CONCENTRATING HORMONE RECEPTOR LIGANDS: SUBSTITUTED 1-BENZYL-4-ARYL PIPERAZINE ANALOGUES | NEUROGEN CORPORATION (US) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002094799-A2 | MELANIN CONCENTRATING HORMONE RECEPTOR LIGANDS: SUBSTITUTED 1-BENZYL-4-ARYL PIPERAZINE ANALOGUES | NEUROGEN CORPORATION (US) | 2002-11-28 | — | — | WO | disclosed |