Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.46 |
| ▸ | FASN | P49327 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 4/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.37 |
| ▸ | VNN1 | O95497 | 1/20 | 0.36 |
| ▸ | MERTK | Q12866 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6637 | 1.00 | KMT2A (0.52) | KMT2AKAT2BFASNMAPTLMNA | |
| SCHEMBL5913 | 0.92 | KMT2A (0.44) | KMT2AKAT2BFASNMAPTLMNA | |
| SCHEMBL5915 | 0.92 | KMT2A (0.44) | KMT2AKAT2BFASNMAPTLMNA | |
| SCHEMBL6261 | 0.85 | KAT2B (0.44) | KMT2AKAT2BMAPTLMNARAB9A | |
| SCHEMBL6263 | 0.85 | KAT2B (0.44) | KMT2AKAT2BMAPTLMNARAB9A | |
| SCHEMBL5906 | 0.85 | NPY5R (0.42) | KMT2AFASNMAPTHCAR3MAPK1 | |
| SCHEMBL5904 | 0.85 | NPY5R (0.42) | KMT2AFASNMAPTHCAR3MAPK1 | |
| SCHEMBL6060 | 0.84 | FASN (0.44) | FASNKDM1AUSP30KCNH2VNN1 | |
| SCHEMBL6062 | 0.84 | FASN (0.44) | FASNKDM1AUSP30KCNH2VNN1 | |
| SCHEMBL7663 | 0.82 | ALDH1A1 (0.51) | KMT2AMAPTLMNARAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493310-A1 | BENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS | GlaxoSmithKline LLC (US) | 2012-09-05 | — | — | EP | disclosed |
| US-20120208827-A1 | BENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC | 2012-08-16 | — | — | US | disclosed |
| WO-2011056635-A1 | BENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2011-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120208827-A1 | BENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS | FASN, FADS1, FADS2 | KMT2A 2560/4885KAT2B 1583/4885FASN 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.