SCHEMBL6635158

SCHEMBL6635158

O=S(=O)(F)c1ccc(OC(F)=C(F)F)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 3/20 0.41
POLB P06746 2/20 0.41
MAPT P10636 1/20 0.41
ELANE P08246 2/20 0.38
F2 P00734 2/20 0.37
TMPRSS4 Q9NRS4 2/20 0.37
CYP1A2 P05177 2/20 0.37
TP53 P04637 1/20 0.37
CYP2D6 P10635 1/20 0.37
TSHR P16473 1/20 0.37
ALDH1A1 P00352 3/20 0.33
KMT2A Q03164 1/20 0.33
HTT P42858 1/20 0.33
CA1 P00915 3/20 0.32
CA2 P00918 3/20 0.32
MMP1 P03956 1/20 0.32
MMP2 P08253 1/20 0.32
MMP9 P14780 1/20 0.32
MMP8 P22894 1/20 0.32
MMP13 P45452 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1505805 0.86 PKM (0.57) PKMPOLBMAPTELANETSHR
SCHEMBL6635239 0.82 ALDH1A1 (0.40) PKMPOLBMAPTELANEALDH1A1
SCHEMBL13922302 0.81 MMP2 (0.42) PKMPOLBMAPTELANEF2
SCHEMBL6632013 0.80
SCHEMBL4530562 0.80 RAB9A (0.35) PKMPOLBMAPTELANEALDH1A1
SCHEMBL6635153 0.78 NSD2 (0.39) MAPTELANEKMT2ACA1CA2
SCHEMBL13922721 0.75 MMP2 (0.38) PKMPOLBMAPTELANEF2
SCHEMBL12833375 0.73 KIF11 (0.39) TP53KMT2AGAASMN1; SMN2
SCHEMBL1505815 0.73 KIF11 (0.39) TP53KMT2AGAASMN1; SMN2
SCHEMBL12833374 0.73 KMT2A (0.43) MAPTELANEF2CYP2D6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8697824-B2 Cross-linkable bi-sulphonyl derivatives and their uses for preparing ion-exchanging membranes HYDRO QUEBEC (CA) 2014-04-15 US disclosed
EP-1286961-B1 SULFONATED PERFLUOROVINYL FUNCTIONAL MONOMERS 3M INNOVATIVE PROPERTIES CO (US) 2004-05-19 EP disclosed
EP-1286961-A1 SULFONATED PERFLUOROVINYL FUNCTIONAL MONOMERS 3M Innovative Properties Company (US) 2003-03-05 EP disclosed
US-6384167-B2 MECHANICAL PROPERTIES ALONG WITH A DESIRABLE LEVEL OF IONIC CONDUCTIVITY; ION-EXCHANGE MEMBRANES 3M INNOVATIVE PROPERTIES COMPANY 2002-05-07 US disclosed
US-20020007083-A1 Sulfonated perfluorovinyl functional monomers 3M INNOVATIVE PROPERTIES COMPANY 2002-01-17 US disclosed
WO-2001094305-A1 SULFONATED PERFLUOROVINYL FUNCTIONAL MONOMERS 3M INNOVATIVE PROPERTIES COMPANY (US) 2001-12-13 WO disclosed
US-6268532-B1 USED FOR PREPARING SULFONATED OR NON-SULFONATED BLOCK POLYMERS 3M INNOVATIVE PROPERTIES COMPANY 2001-07-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020007083-A1 Sulfonated perfluorovinyl functional monomers AFF2, AFF1, FOS PKM 3550/4885POLB 3080/4885MAPT 4365/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.