Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 2/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.38 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6635865 | 0.87 | BACE1 (0.42) | FOLH1GABRA5S1PR1BACE1TACR1 | |
| SCHEMBL6637281 | 0.85 | HSP90AA1 (0.49) | FOLH1S1PR1TACR1S1PR3FABP4 | |
| SCHEMBL6637411 | 0.80 | LTB4R (0.43) | FOLH1GABRA5S1PR1TACR1S1PR3 | |
| SCHEMBL6682318 | 0.77 | TAS2R14 (0.50) | FOLH1GABRA5S1PR1TACR1S1PR3 | |
| SCHEMBL6639317 | 0.77 | CFTR (0.44) | S1PR1EPHX2PLK1 | |
| SCHEMBL6638442 | 0.76 | CYP3A4 (0.44) | S1PR1EPHX2TACR1PLK1 | |
| SCHEMBL6639868 | 0.75 | PRKAB2 (0.44) | FOLH1FABP4PTPN1 | |
| SCHEMBL5788411 | 0.74 | ALDH1A1 (0.53) | S1PR1BACE1 | |
| SCHEMBL28776910 | 0.73 | BCAT2 (0.45) | S1PR1TACR1S1PR3PLK1HSP90AA1 | |
| SCHEMBL8070699 | 0.72 | TAS2R14 (0.47) | S1PR1S1PR3FABP4PLK1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383760-A1 | BIARYLCARBOXAMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002090347-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |