Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.42 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | POLQ | O75417 | 2/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | HNF4A | P41235 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6637890 | 0.85 | FOLH1 (0.43) | HSP90AA1HSP90AB1FOLH1DCLRE1ADCLRE1B | |
| SCHEMBL6635865 | 0.83 | BACE1 (0.42) | FOLH1DCLRE1ADCLRE1BFABP4S1PR1 | |
| SCHEMBL6637411 | 0.83 | LTB4R (0.43) | FOLH1S1PR1POLQTACR1S1PR3 | |
| SCHEMBL6639868 | 0.80 | PRKAB2 (0.44) | FOLH1FABP4PTPN1AKR1C2AKR1C1 | |
| SCHEMBL6682318 | 0.80 | TAS2R14 (0.50) | FOLH1FABP4PTPN1S1PR1TACR1 | |
| SCHEMBL28776910 | 0.78 | BCAT2 (0.45) | HSP90AA1HSP90AB1S1PR1TACR1PLK1 | |
| SCHEMBL16529172 | 0.76 | KDM4E (0.47) | HSP90AA1HSP90AB1POLQ | |
| Phthalic Acid SCHEMBL3628700 | 0.76 | ALDH1A1 (0.50) | FOLH1FABP4POLQAKR1C3AKR1C2 | |
| SCHEMBL28087913 | 0.75 | TRPV1 (0.41) | HSP90AA1HSP90AB1S1PR1POLQTACR1 | |
| SCHEMBL6639317 | 0.74 | CFTR (0.44) | S1PR1PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383760-A1 | BIARYLCARBOXAMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002090347-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |