Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.40 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 2/20 | 0.39 |
| ▸ | BMP1 | P13497 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9868832 | 0.72 | SIGMAR1 (0.39) | — | |
| SCHEMBL6648243 | 0.71 | SIGMAR1 (0.36) | — | |
| Hydrochloric Acid SCHEMBL6586236 | 0.69 | HTR2C (0.41) | TP53MAPK1 | |
| SCHEMBL9726244 | 0.69 | HTR7 (0.50) | HTR7 | |
| SCHEMBL6648602 | 0.69 | SIGMAR1 (0.36) | — | |
| SCHEMBL5189511 | 0.67 | ESR1 (0.80) | ESR1LMNAALOX5NR1I2PTGES | |
| SCHEMBL6648237 | 0.67 | LMNA (0.41) | LMNA | |
| SCHEMBL5265951 | 0.66 | POLB (0.44) | KMT2A | |
| SCHEMBL10849078 | 0.66 | ALDH1A1 (0.39) | LMNATSHRKMT2AHSD17B10 | |
| SCHEMBL10851305 | 0.65 | ALDH1A1 (0.38) | LMNATSHRKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130313-A | Central nervous system disorders, cardiovascular disorders or gastrointestinal disorders | RHONE-POULENC SANTE (FR) | 1992-07-14 | — | — | US | disclosed |