Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | SCN4A | P35499 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | SCN1A | P35498 | 2/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.31 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6652404 | 0.82 | CA1 (0.30) | CA1CA2CA7CA9TAAR1 | |
| SCHEMBL13027745 | 0.80 | TAAR1 (0.31) | TAAR1HTR1DSCN4ALMNASCN1A | |
| SCHEMBL10710923 | 0.80 | NOS2 (0.40) | TAAR1HTR1DSCN4ALMNASCN1A | |
| SCHEMBL13027651 | 0.77 | NPBWR1 (0.32) | LMNANPBWR1MEN1MAPTKMT2A | |
| SCHEMBL13027818 | 0.76 | CYP1A2 (0.33) | CA1CA2CA7CA9SCN4A | |
| SCHEMBL5346547 | 0.75 | CA1 (0.48) | CA1CA2CA7CA9TAAR1 | |
| SCHEMBL730149 | 0.75 | PSMD14 (0.32) | CA1CA2CA7CA9CYP1A2 | |
| SCHEMBL988627 | 0.74 | TRPA1 (0.39) | CA1CA2CA7CA9SCN4A | |
| SCHEMBL106098 | 0.73 | TSHR (0.43) | CA1CA2CA7CA9SCN4A | |
| SCHEMBL13027106 | 0.72 | HSP90AA1 (0.36) | CA1CA2CA7CA9SCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663358-A | Process for the preparation of organosilicon disulfide compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-09-02 | — | — | US | claimed |
| EP-0785206-A1 | Process for the preparation of organosilicon disulfide compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-07-23 | — | — | EP | claimed |
| EP-1178077-B1 | The preparation of surface modified silica | GOODYEAR TIRE & RUBBER (US) | 2004-06-16 | — | — | EP | disclosed |
| US-6727374-B2 | TRIALKOXYSILYLHYDROCARBYL CYCLOHEXYL DISULFIDE, MADE BY REACTING N-CYCLOHEXYLTHIOPHTHALIMIDE AND A MERCAPTOALKOXYSILANE; SULFUR VULCANIZED RUBBER TIRES, BELTS AND HOSES | THE GOODYEAR TIRE & RUBBER COMPANY | 2004-04-27 | — | — | US | disclosed |
| US-6593433-B2 | Alkoxysilylalkylammonium salts of alkoxysilylalkyl mercaptans used for processing sulfur-vuncanizable rubber compositions containing fillers | THE GOODYEAR TIRE & RUBBER COMPANY | 2003-07-15 | — | — | US | disclosed |
| US-6465670-B2 | SURFACE TREATMENT USING ORGANOSILICON COMPOUND, SOLVENT AND PHASE TRANSFER CATALYST | THE GOODYEAR TIRE & RUBBER COMPANY | 2002-10-15 | — | — | US | disclosed |
| US-20020022085-A1 | Preparation of surface modified silica | GOODYEAR TIRE & RUBBER COMPANY, THE | 2002-02-21 | — | — | US | disclosed |
| EP-1178077-A1 | The preparation of surface modified silica | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2002-02-06 | — | — | EP | disclosed |
| US-20020010239-A1 | Siloxy containing salt compounds | GOODYEAR TIRE & RUBBER COMPANY, THE | 2002-01-24 | — | — | US | disclosed |
| US-20010056142-A1 | Asymmetrical siloxy disulfide compounds | THE GOODYEAR TIRE & RUBBER COMPANY. | 2001-12-27 | — | — | US | disclosed |
| US-6300397-B1 | MIXING SULFUR VULCANIZABLE ELASTOMER SELECTED FROM CONJUGATED DIENE HOMOPOLYMERS AND COPOLYMERS AND FROM COPOLYMERS OF CONJUGATED DIENE AND AROMATIC VINYL COMPOUND, PARTICULATE PRECIPITATED SILICA, SILOXY CYCLOHEXYL DISULFIDE COMPOUND | THE GOODYEAR TIRE & RUBBER COMPANY | 2001-10-09 | — | — | US | disclosed |
| US-5760110-A | Process for the preparation of a particular reinforced rubber composition | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1998-06-02 | — | — | US | disclosed |
| EP-0794221-A1 | Process for the preparation of a particulate reinforced rubber composition | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-09-10 | — | — | EP | disclosed |
| US-5663358-A | Process for the preparation of organosilicon disulfide compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-09-02 | — | — | US | disclosed |
| EP-0785206-A1 | Process for the preparation of organosilicon disulfide compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-07-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010056142-A1 | Asymmetrical siloxy disulfide compounds | SULT1A1, QSOX1, TST | CA1 2163/4885CA2 2043/4885CA7 3481/4885 |
| US-20020022085-A1 | Preparation of surface modified silica | OSTC, SAMM50, SSRP1 | CA1 447/4885CA2 2429/4885CA7 1080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.