Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GPX4 | P36969 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | HCK | P08631 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6665957 | 0.99 | GAA (0.41) | GAAALDH1A1MAPTKDM4EMAPK1 | |
| Hydrochloric Acid SCHEMBL6665463 | 0.80 | ALDH1A1 (0.36) | GAAALDH1A1MAPTKDM4EL3MBTL1 | |
| SCHEMBL6659051 | 0.80 | TUBB4A (0.42) | GAAALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL6663221 | 0.80 | MAOA (0.37) | GAAALDH1A1MAPTKDM4EKDR | |
| Hydrochloric Acid SCHEMBL6659746 | 0.79 | MAOA (0.36) | GAAALDH1A1MAPTKDM4EKDR | |
| SCHEMBL6659417 | 0.79 | MEN1 (0.36) | GAAALDH1A1MAPTKDM4EMAPK1 | |
| SCHEMBL6660415 | 0.79 | MAPT (0.43) | GAAALDH1A1MAPTKDM4EMAPK1 | |
| Hydrochloric Acid SCHEMBL6663229 | 0.78 | MAPT (0.36) | GAAALDH1A1MAPTKDM4EMAPK1 | |
| Hydrochloric Acid SCHEMBL6660447 | 0.78 | DHFR (0.42) | GAAALDH1A1MAPTKDM4EMAPK1 | |
| SCHEMBL6661033 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1232509-C | Diaminopyrazole derivatives and dyes containing these compounds | P & G KRYROER CO (US) | 2005-12-21 | — | — | CN | claimed |
| EP-1268436-B1 | NOVEL DIAMINOPYRAZOLE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS | WELLA AG (DE) | 2004-08-18 | — | — | EP | claimed |
| CN-1441786-A | Novel diamino pyrazole derivatives and dyes containing said compounds | WELLA AG (DE) | 2003-09-10 | — | — | CN | claimed |
| US-6600050-B2 | Inorganic and organic acids and agents, containing these compounds, for the oxidative dyeing of fibers such as hair for hair dyes | WELLA AG (DE) | 2003-07-29 | — | — | US | claimed |
| US-20030115684-A1 | Novel diaminopyrazole derivatives and dyes containing said compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-06-26 | — | — | US | claimed |
| EP-1268436-A1 | NOVEL DIAMINOPYRAZOLE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2003-01-02 | — | — | EP | claimed |
| WO-2002072556-A1 | NOVEL DIAMINOPYRAZOLE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2002-09-19 | — | — | WO | claimed |
| CN-1232509-C | Diaminopyrazole derivatives and dyes containing these compounds | P & G KRYROER CO (US) | 2005-12-21 | — | — | CN | disclosed |
| EP-1268436-B1 | NOVEL DIAMINOPYRAZOLE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS | WELLA AG (DE) | 2004-08-18 | — | — | EP | disclosed |
| CN-1441786-A | Novel diamino pyrazole derivatives and dyes containing said compounds | WELLA AG (DE) | 2003-09-10 | — | — | CN | disclosed |
| US-6600050-B2 | Inorganic and organic acids and agents, containing these compounds, for the oxidative dyeing of fibers such as hair for hair dyes | WELLA AG (DE) | 2003-07-29 | — | — | US | disclosed |
| US-20030115684-A1 | Novel diaminopyrazole derivatives and dyes containing said compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-06-26 | — | — | US | disclosed |
| EP-1268436-A1 | NOVEL DIAMINOPYRAZOLE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2003-01-02 | — | — | EP | disclosed |
| WO-2002072556-A1 | NOVEL DIAMINOPYRAZOLE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2002-09-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030115684-A1 | Novel diaminopyrazole derivatives and dyes containing said compounds | AOC1, DPYD, PPOX | GAA 1099/4885ALDH1A1 128/4885MAPT 349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.