Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | TOP2A | P11388 | 2/20 | 0.42 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7889768 | 0.82 | KMT2A (0.59) | ALDH1A1KDM4ELMNAHSD17B10HPGD | |
| SCHEMBL8091157 | 0.82 | KDM4E (0.42) | ALDH1A1DRD3KDM4ELMNAHSD17B10 | |
| SCHEMBL30181414 | 0.77 | ALDH1A1 (0.39) | ALDH1A1DRD3KDM4ELMNAHSD17B10 | |
| SCHEMBL9008350 | 0.77 | ALDH1A1 (0.39) | ALDH1A1DRD3KDM4ELMNAHSD17B10 | |
| SCHEMBL9626497 | 0.77 | ALDH1A1 (0.41) | ALDH1A1DRD3KDM4ELMNAHSD17B10 | |
| SCHEMBL9381103 | 0.76 | LMNA (0.50) | ALDH1A1DRD3KDM4ELMNAHSD17B10 | |
| SCHEMBL29442121 | 0.74 | KDM4E (0.69) | ALDH1A1KDM4ELMNAHSD17B10HPGD | |
| SCHEMBL501238 | 0.74 | KDM4E (0.69) | ALDH1A1KDM4ELMNAHSD17B10HPGD | |
| SCHEMBL6217085 | 0.74 | KMT2A (0.46) | ALDH1A1DRD3KDM4ELMNAHSD17B10 | |
| SCHEMBL3976539 | 0.73 | CHRM1 (0.37) | ALDH1A1KDM4ELMNAHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3784656-B1 | PROCESS FOR THE HYDROLYSIS OF QUINOLONE CARBOXYLIC ESTERS | ELANCO ANIMAL HEALTH GMBH (DE) | 2023-06-28 | — | — | EP | claimed |
| US-11332444-B2 | Method for the hydrolysis of quinolonecarboxylic esters | BAYER ANIMAL HEALTH GMBH (DE) | 2022-05-17 | — | — | US | claimed |
| US-20210078950-A1 | METHOD FOR THE HYDROLYSIS OF QUINOLONECARBOXYLIC ESTERS | ELANCO ANIMAL HEALTH GMBH (DE) | 2021-03-18 | — | — | US | claimed |
| EP-1236718-B1 | Improved process for the preparation of fluoro-quinolonecarboxylic acids | BAYER CHEMICALS AG (DE) | 2004-08-11 | — | — | EP | claimed |
| US-6590101-B2 | Hydrolysis of the corresponding C1-C4-alkyl esters with addition of water, acetic acid, and sulfuric acid using a drastically reduced amount of sulfuric acid | BAYER AKTIENGESELLSCHAFT (DE) | 2003-07-08 | — | — | US | claimed |
| US-20020120138-A1 | Process for the preparation of fluoroquinolonecarboxylic acids | LANXESS DEUTSCHLAND GMBH (DE) | 2002-08-29 | — | — | US | claimed |
| EP-3784656-B1 | PROCESS FOR THE HYDROLYSIS OF QUINOLONE CARBOXYLIC ESTERS | ELANCO ANIMAL HEALTH GMBH (DE) | 2023-06-28 | — | — | EP | disclosed |
| US-11332444-B2 | Method for the hydrolysis of quinolonecarboxylic esters | BAYER ANIMAL HEALTH GMBH (DE) | 2022-05-17 | — | — | US | disclosed |
| US-20210078950-A1 | METHOD FOR THE HYDROLYSIS OF QUINOLONECARBOXYLIC ESTERS | ELANCO ANIMAL HEALTH GMBH (DE) | 2021-03-18 | — | — | US | disclosed |
| US-6590101-B2 | Hydrolysis of the corresponding C1-C4-alkyl esters with addition of water, acetic acid, and sulfuric acid using a drastically reduced amount of sulfuric acid | BAYER AKTIENGESELLSCHAFT (DE) | 2003-07-08 | — | — | US | disclosed |
| US-20020120138-A1 | Process for the preparation of fluoroquinolonecarboxylic acids | LANXESS DEUTSCHLAND GMBH (DE) | 2002-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020120138-A1 | Process for the preparation of fluoroquinolonecarboxylic acids | ADH1C, CTRC, ADH1A | ALDH1A1 124/4885DRD3 1628/4885KDM4E 2934/4885 |
| US-20210078950-A1 | METHOD FOR THE HYDROLYSIS OF QUINOLONECARBOXYLIC ESTERS | NQO2, PGD, ALAD | ALDH1A1 274/4885DRD3 2330/4885KDM4E 2839/4885 |
| US-11332444-B2 | Method for the hydrolysis of quinolonecarboxylic esters | NQO2, PGD, ALAD | ALDH1A1 274/4885DRD3 2330/4885KDM4E 2839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.