SCHEMBL6662487

SCHEMBL6662487

CS(=O)(=O)C(=O)Nc1ccc(F)c([Ti](C2=CC=CC2)(C2=CC=CC2)c2c(F)ccc(NC(=O)S(C)(=O)=O)c2F)c1F

nearest known ligand 0.30

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.30
CA2 P00918 2/20 0.30
CA9 Q16790 2/20 0.30
CA12 O43570 1/20 0.30
TP53 P04637 1/20 0.30
NPC1 O15118 1/20 0.30
ALPL P05186 1/20 0.30
ALPI P09923 1/20 0.30
ALPG P10696 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL483069 0.85 HDAC1 (0.39) CA1CA2CA9NPC1ALPL
SCHEMBL267063 0.83 KDM1A (0.33)
SCHEMBL483181 0.82 NPC1 (0.40) TP53NPC1
SCHEMBL483118 0.82 KDM4E (0.35) NPC1ALPLALPIALPG
SCHEMBL269422 0.82 PDK1 (0.34) NPC1ALPLALPIALPG
SCHEMBL483079 0.82 HTT (0.47) TP53NPC1ALPLALPIALPG
SCHEMBL483279 0.82 ALPL (0.38) TP53ALPLALPIALPG
SCHEMBL482491 0.80 RAB9A (0.44) TP53NPC1
SCHEMBL483155 0.80 ALDH1A1 (0.38) TP53ALPLALPIALPG
SCHEMBL483207 0.80 HTT (0.34) CA1CA2CA9NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1091247-B1 Photopolymerizable composition FUJI PHOTO FILM CO LTD (JP) 2004-08-25 EP disclosed
EP-1091247-A2 Photopolymerizable composition FUJI PHOTO FILM CO., LTD. (JP) 2001-04-11 EP disclosed
US-6153660-A VERY HIGH SENSITIVITY TO BEAMS IN THE VISIBLE REGION, PARTICULARLY TO VISIBLE RAYS AT 400 NM OR MORE SUCH AS RAYS AT 488 NM OR 532 NM CORRESPONDING TO THE OUTPUT OF AR+ LASER OR YAG-SHG LASER FUJI PHOTO FILM CO., LTD. (JP) 2000-11-28 US disclosed
EP-0924570-A1 Photopolymerizable composition FUJI PHOTO FILM CO., LTD. (JP) 1999-06-23 EP disclosed