Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6681189 | 0.87 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2HTTHPGDNPSR1 | |
| SCHEMBL6664310 | 0.81 | ALDH1A1 (0.53) | ALDH1A1HPGDNPSR1CHRM3KMT2A | |
| SCHEMBL6665368 | 0.81 | NPSR1 (0.52) | ALDH1A1HPGDNPSR1CHRM3KMT2A | |
| SCHEMBL6669041 | 0.80 | ALDH1A1 (0.48) | ALDH1A1LMNAHPGDNPSR1CHRM3 | |
| SCHEMBL6664922 | 0.80 | NPSR1 (0.48) | ALDH1A1HPGDNPSR1CHRM3KMT2A | |
| SCHEMBL6665392 | 0.79 | ALDH1A1 (0.51) | ALDH1A1HPGDNPSR1CHRM3KMT2A | |
| SCHEMBL6680489 | 0.74 | KMT2A (0.49) | LMNAHTTNPSR1CHRM3KMT2A | |
| SCHEMBL6663062 | 0.74 | GAA (0.48) | ALDH1A1SMN1; SMN2CHRM3KMT2A | |
| SCHEMBL6663170 | 0.74 | CHRM3 (0.67) | ALDH1A1CHRM3 | |
| SCHEMBL6665574 | 0.73 | MEN1 (0.57) | ALDH1A1LMNASMN1; SMN2HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014425-A1 | ACTIVATORS OF SMALL CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNELS AND USE THEREOF | GLAXO GROUP LIMITED (GB) | 2004-02-19 | — | — | WO | disclosed |