Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.56 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6664310 | 0.78 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1MAPTCYP2C9 | |
| SCHEMBL6665392 | 0.77 | ALDH1A1 (0.51) | MEN1KMT2AGAAALDH1A1POLB | |
| SCHEMBL6665368 | 0.76 | NPSR1 (0.52) | MEN1KMT2AALDH1A1MAPTCYP2C9 | |
| SCHEMBL6663170 | 0.75 | CHRM3 (0.67) | ALDH1A1 | |
| SCHEMBL6681189 | 0.74 | ALDH1A1 (0.61) | MEN1KMT2AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL6669041 | 0.74 | ALDH1A1 (0.48) | KMT2AALDH1A1MAPTLMNACYP2C9 | |
| SCHEMBL6664922 | 0.74 | NPSR1 (0.48) | KMT2AALDH1A1POLBMAPTCYP2C9 | |
| SCHEMBL6664323 | 0.73 | ALDH1A1 (0.50) | KMT2AALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL6680489 | 0.72 | KMT2A (0.49) | MEN1KMT2AGAAMAPTLMNA | |
| SCHEMBL19002724 | 0.68 | MEN1 (0.68) | MEN1KMT2AGAAALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014425-A1 | ACTIVATORS OF SMALL CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNELS AND USE THEREOF | GLAXO GROUP LIMITED (GB) | 2004-02-19 | — | — | WO | disclosed |