Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.53 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.49 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6661201 | 0.90 | FLT3 (0.58) | KDM4EMEN1KMT2ANPC1RAB9A | |
| SCHEMBL6657213 | 0.84 | FLT3 (0.54) | KDM4EMEN1KMT2ANPC1RAB9A | |
| SCHEMBL6657806 | 0.84 | DRD2 (0.54) | KDM4EMEN1KMT2ANPC1RAB9A | |
| SCHEMBL6661461 | 0.79 | ROCK2 (0.59) | KDM4EMEN1KMT2ANPC1RAB9A | |
| SCHEMBL6657726 | 0.78 | GAA (0.53) | KDM4EMEN1KMT2ANPC1RAB9A | |
| SCHEMBL2760020 | 0.78 | KDM4E (0.58) | KDM4EMEN1KMT2ASRD5A2SRD5A1 | |
| SCHEMBL6657486 | 0.78 | MTNR1A (0.57) | KDM4EMEN1KMT2ANPC1RAB9A | |
| SCHEMBL6656183 | 0.78 | MTNR1A (0.57) | KDM4EMEN1KMT2ANPC1RAB9A | |
| SCHEMBL2735969 | 0.77 | CA12 (0.72) | KDM4EMEN1KMT2ANPC1RAB9A | |
| SCHEMBL3928684 | 0.77 | FLT3 (0.52) | KDM4EMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1440966-A1 | Indole derivatives useful for the treatment of diseases | Pfizer Limited (GB) | 2004-07-28 | — | — | EP | disclosed |