Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.53 |
| ▸ | MGAM | O43451 | 4/20 | 0.53 |
| ▸ | SI | P14410 | 4/20 | 0.53 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | MIF | P14174 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMO | Q99835 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6657213 | 0.87 | FLT3 (0.54) | GAAMGAMSIMGAM2MEN1 | |
| SCHEMBL6661201 | 0.86 | FLT3 (0.58) | GAAMEN1KMT2APOLBKDM4E | |
| SCHEMBL6657806 | 0.84 | DRD2 (0.54) | GAAMGAMSIMGAM2MEN1 | |
| SCHEMBL17206255 | 0.82 | MEN1 (0.60) | GAAMGAMSIMGAM2MEN1 | |
| SCHEMBL6657486 | 0.80 | MTNR1A (0.57) | GAAMEN1KMT2APOLBKDM4E | |
| SCHEMBL6661461 | 0.79 | ROCK2 (0.59) | GAAMEN1KMT2APOLBKDM4E | |
| SCHEMBL6664487 | 0.78 | KDM4E (0.55) | MEN1KMT2APOLBKDM4ENPC1 | |
| SCHEMBL4108942 | 0.76 | PDGFRB (0.58) | MEN1KMT2AKDM4EALDH1A1SMO | |
| SCHEMBL6656183 | 0.76 | MTNR1A (0.57) | GAAMEN1KMT2APOLBKDM4E | |
| SCHEMBL6661736 | 0.76 | KDM4E (0.64) | GAAMGAMSIMGAM2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1440966-A1 | Indole derivatives useful for the treatment of diseases | Pfizer Limited (GB) | 2004-07-28 | — | — | EP | disclosed |