Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 5/20 | 0.61 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.61 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.61 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.61 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.61 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | DRD1 | P21728 | 2/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.61 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.61 |
| ▸ | DRD3 | P35462 | 2/20 | 0.61 |
| ▸ | HTR1A | P08908 | 2/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | HTR7 | P34969 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | BLM | P54132 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21061259 | 0.84 | GRM4 (0.44) | HIF1AADRB2ADRB1ADRA2AADRB3 | |
| SCHEMBL9706046 | 0.84 | TSHR (0.58) | HIF1AADRB2ADRB1ADRB3TSHR | |
| SCHEMBL6680502 | 0.84 | HIF1A (0.63) | HIF1AADRB2ADRB1ADRA2AADRB3 | |
| SCHEMBL14535391 | 0.84 | FAAH (0.45) | HIF1AADRB2ADRB1ADRA2AADRB3 | |
| SCHEMBL10606401 | 0.83 | ADRB2 (0.50) | HIF1AADRB2ADRB1TSHRADRA1A | |
| SCHEMBL9646909 | 0.81 | LMNA (0.52) | HIF1ALMNADRD2ADRA1DGRM4 | |
| SCHEMBL6540746 | 0.80 | S1PR1 (0.45) | TSHRCYP3A4GRM4FAAHSLC6A2 | |
| SCHEMBL4697927 | 0.80 | S1PR1 (0.45) | TSHRCYP3A4GRM4FAAHSLC6A2 | |
| SCHEMBL8949484 | 0.80 | GSK3B (0.49) | TSHRMAPTALDH1A1GRM4FAAH | |
| SCHEMBL6481575 | 0.80 | S1PR1 (0.45) | TSHRCYP3A4GRM4FAAHSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116464-A1 | Aryl-ethanolamine derivatives as antiviral agents | PHARMACIA & UPJOHN COMPANY | 2004-06-17 | — | — | US | disclosed |
| WO-2004022568-A1 | ARYL-ETHANOLAMINE DERIVATIVES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-18 | — | — | WO | disclosed |