Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | GALR3 | O60755 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6666064 | 0.84 | HIF1A (0.61) | HIF1ALMNAGALR3KMT2AKDM4E | |
| SCHEMBL9646909 | 0.82 | LMNA (0.52) | HIF1ALMNAGALR3S1PR1GRM4 | |
| SCHEMBL9706046 | 0.82 | TSHR (0.58) | HIF1ALMNAKMT2AKDM4EADRB2 | |
| SCHEMBL14535391 | 0.81 | FAAH (0.45) | HIF1ALMNAGALR3KDM4EL3MBTL1 | |
| SCHEMBL9647484 | 0.81 | HIF1A (0.49) | HIF1ALMNAGALR3KMT2AKDM4E | |
| SCHEMBL10606401 | 0.81 | ADRB2 (0.50) | HIF1ALMNAKMT2AKDM4EADRB2 | |
| SCHEMBL12056784 | 0.80 | GRM4 (0.44) | TSHRNFKB1DRD3S1PR1GRM4 | |
| SCHEMBL19707534 | 0.78 | GRM4 (0.43) | KDM4EDRD3S1PR1GRM4 | |
| Etilefrine SCHEMBL150802 | 0.78 | HIF1A (1.00) | HIF1ALMNAGALR3KMT2AKDM4E | |
| Etilefrine SCHEMBL30510958 | 0.78 | HIF1A (1.00) | HIF1ALMNAGALR3KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022568-A1 | ARYL-ETHANOLAMINE DERIVATIVES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-18 | — | — | WO | disclosed |