Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MDH2 | P40926 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | APAF1 | O14727 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6664683 | 0.89 | KMT2A (0.43) | KMT2AMAPTMEN1LMNAMDH2 | |
| SCHEMBL6666692 | 0.81 | PRKAG1 (0.45) | KMT2AMAPTMEN1LMNAHPGD | |
| SCHEMBL6663006 | 0.81 | PRKAG1 (0.40) | KMT2AMAPTMEN1LMNAHPGD | |
| SCHEMBL6670369 | 0.79 | PRKAG1 (0.43) | KMT2AMAPTMEN1LMNAHPGD | |
| SCHEMBL6665669 | 0.77 | CPT2 (0.43) | KMT2AMEN1HPGDTP53CYP1A2 | |
| SCHEMBL6668559 | 0.76 | NNMT (0.41) | LMNATSHRPRKAG1PRKAA2PRKAB1 | |
| SCHEMBL6669305 | 0.76 | PRKAG1 (0.41) | LMNATSHRPRKAG1PRKAA2PRKAB1 | |
| SCHEMBL6668468 | 0.76 | KDM5A (0.41) | TP53PRKAG1PRKAA2PRKAB1 | |
| SCHEMBL6665535 | 0.76 | KDM5A (0.41) | PRKAG1PRKAA2PRKAB1 | |
| SCHEMBL6667091 | 0.75 | CTRB1 (0.39) | KMT2AMEN1HPGDTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014388-A1 | 6,6-FUSED HETEROARYL DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | disclosed |