SCHEMBL667078

SCHEMBL667078

CC(N)Cn1ccc(=O)[nH]c1=O

nearest known ligand 0.61

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.61
CRBN Q96SW2 2/20 0.46
DUT P33316 5/20 0.45
HTR2C P28335 7/20 0.43
L3MBTL1 Q9Y468 1/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
HTR2A P28223 5/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14478216 1.00 PKM (0.61) PKMCRBNDUTHTR2CL3MBTL1
SCHEMBL7133033 0.85 PKM (0.65) PKMCRBNDUTL3MBTL1ALDH1A1
SCHEMBL9694561 0.83 PKM (0.54) PKMCRBNDUTL3MBTL1
SCHEMBL27608399 0.81 PKM (0.59) PKMCRBNDUTL3MBTL1ALDH1A1
(S)-Willardiine SCHEMBL438494 0.78 GRIA1 (0.56) PKMDUTALDH1A1LMNA
(S)-Willardiine SCHEMBL401191 0.78 GRIA1 (0.56) PKMDUTALDH1A1LMNA
SCHEMBL7136481 0.78 PKM (0.56) PKMCRBNDUTALDH1A1LMNA
SCHEMBL23873265 0.78 PKM (0.60) PKMCRBNDUTL3MBTL1ALDH1A1
SCHEMBL26916421 0.78 PKM (0.60) PKMCRBNDUTL3MBTL1ALDH1A1
SCHEMBL28198563 0.77 PKM (0.58) PKMCRBNDUTALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 639 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260138999-A1 REAGENTS AND THEIR USE FOR MODULAR ENANTIODIVERGENT SYNTHESIS OF C-P BONDS BRISTOL MYERS SQUIBB CO (US) 2026-05-21 US disclosed
WO-2026106956-A1 DISULFIDE-STABILIZED NOROVIRUS VIRUS-LIKE PARTICLE DESIGN MERCK SHARP & DOHME LLC (US) 2026-05-21 WO disclosed
US-12629412-B2 Betacoronavirus mRNA vaccines MODERNATX, INC. (US) 2026-05-19 US disclosed
US-20260130985-A1 NUCLEIC ACID-BASED UNIVERSAL VACCINE AND METHODS OF USE THEREOF ADVANCED RNA VACCINE ARV TECH INC (US) 2026-05-14 US disclosed
US-12622960-B2 Varicella zoster virus (VZV) vaccine MODERNATX, INC. (US) 2026-05-12 US disclosed
US-20260108595-A1 BETACORONAVIRUS mRNA VACCINES MODERNATX, INC. (US) 2026-04-23 US disclosed
EP-3458081-B1 POLYNUCLEOTIDES ENCODING CITRIN FOR THE TREATMENT OF CITRULLINEMIA TYPE 2 MODERNATX INC (US) 2026-04-15 EP disclosed
US-20260097110-A1 BETACORONAVIRUS mRNA VACCINES MODERNATX, INC. (US) 2026-04-09 US disclosed
US-20260091104-A1 NUCLEIC ACID VACCINES MODERNATX, INC. (US) 2026-04-02 US disclosed
EP-4709417-A2 POLYNUCLEOTIDES ENCODING NOROVIRUS VP1 ANTIGENS AND USES THEREOF Merck Sharp & Dohme LLC (US) 2026-03-18 EP disclosed
US-20120046346-A1 SUSTAINED POLYPEPTIDE EXPRESSION FROM SYNTHETIC, MODIFIED RNAS AND USES THEREOF IMMUNE DISEASE INSTITUTE, INC. (US) 2012-02-23 US disclosed
WO-2011130624-A2 SUSTAINED POLYPEPTIDE EXPRESSION FROM SYNTHETIC, MODIFIED RNAS AND USES THEREOF IMMUNE DISEASE INSTITUTE, INC. (US) 2011-10-20 WO disclosed
WO-2011103137-A1 CELL-BASED METHODS AND REAGENTS ALNYLAM PHARMACEUTICALS, INC. (US) 2011-08-25 WO disclosed
US-20110150894-A1 METHODS OF MODULATING ANGIOGENESIS VIA TRPV4 CHILDREN'S MEDICAL CENTER CORPORATION (US) 2011-06-23 US disclosed
WO-2011005765-A1 BIOPROCESSING ALNYLAM PHARMACEUTICALS, INC. (US) 2011-01-13 WO disclosed
WO-2011005786-A2 COMPOSITIONS AND METHODS FOR ENHANCING PRODUCTION OF A BIOLOGICAL PRODUCT ALNYLAM PHARMACEUTICALS, INC. (US) 2011-01-13 WO disclosed
WO-2011005793-A1 CELL-BASED BIOPROCESSING ALNYLAM PHARMACEUTICALS, INC. (US) 2011-01-13 WO disclosed
WO-2009155504-A9 METHODS FOR THE MODULATION OF ANGIOGENESIS THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2010-04-08 WO disclosed
WO-2009155504-A2 METHODS FOR THE MODULATION OF ANGIOGENESIS THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2009-12-23 WO disclosed
WO-2009149239-A1 METHODS OF MODULATING ANGIOGENESIS VIA TRPV4 CHILDREN'S MEDICAL CENTER CORPORATION (US) 2009-12-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260097110-A1 BETACORONAVIRUS mRNA VACCINES RNMT, RNGTT, METTL16 PKM 2970/4885CRBN 3200/4885DUT 199/4885
US-20260138999-A1 REAGENTS AND THEIR USE FOR MODULAR ENANTIODIVERGENT SYNTHESIS OF C-P BONDS RNGTT, CDA, DCTD PKM 1615/4885CRBN 1816/4885DUT 16/4885
US-12629412-B2 Betacoronavirus mRNA vaccines RNMT, RNGTT, METTL16 PKM 3146/4885CRBN 3187/4885DUT 159/4885
US-20260091104-A1 NUCLEIC ACID VACCINES RNMT, NSUN2, AMPD1 PKM 2560/4885CRBN 3305/4885DUT 66/4885
US-20260108595-A1 BETACORONAVIRUS mRNA VACCINES RNMT, METTL16, NSUN2 PKM 3953/4885CRBN 2520/4885DUT 527/4885
US-12622960-B2 Varicella zoster virus (VZV) vaccine NSUN2, RNMT, RNGTT PKM 4441/4885CRBN 4070/4885DUT 177/4885
US-20260130985-A1 NUCLEIC ACID-BASED UNIVERSAL VACCINE AND METHODS OF USE THEREOF UPF1, NSUN2, CD4 PKM 3964/4885CRBN 2377/4885DUT 567/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.