Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6676265 | 0.89 | CA2 (0.40) | CA1CA2KMT2AALDH1A1MAPT | |
| SCHEMBL6675284 | 0.88 | ESRRG (0.42) | CA1CA2KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8771747 | 0.88 | CA2 (0.39) | CA1CA2MAPTNAMPT | |
| SCHEMBL6676118 | 0.83 | CA2 (0.47) | CA1CA2KMT2AMAPTNAMPT | |
| SCHEMBL6675306 | 0.83 | NQO2 (0.38) | CA1CA2CA12CA9MAPT | |
| SCHEMBL8771555 | 0.81 | IDO1 (0.39) | CA1CA2MAPT | |
| SCHEMBL6675053 | 0.79 | CA1 (0.46) | CA1CA2CA12CA9KMT2A | |
| SCHEMBL903446 | 0.78 | CA12 (0.64) | CA1CA2CA12CA9KMT2A | |
| SCHEMBL31432851 | 0.78 | CA12 (0.64) | CA1CA2CA12CA9KMT2A | |
| SCHEMBL6681999 | 0.75 | MAPT (0.45) | CA1CA2CA12CA9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | disclosed |
| EP-0798292-A1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | Chugai Seiyaku Kabushiki Kaisha (JP) | 1997-10-01 | — | — | EP | disclosed |