Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6675284 | 0.89 | ESRRG (0.42) | CA2CA1PTGER4NAMPTMAPT | |
| SCHEMBL8771747 | 0.89 | CA2 (0.39) | CA2CA1PTGER4NAMPTMAPT | |
| SCHEMBL6682001 | 0.89 | CA1 (0.41) | CA2CA1NAMPTMAPTALDH1A1 | |
| SCHEMBL6676118 | 0.85 | CA2 (0.47) | CA2CA1PTGER4NAMPTMAPT | |
| SCHEMBL6675306 | 0.81 | NQO2 (0.38) | CA2CA1MAPTNQO2KDM4E | |
| SCHEMBL6676127 | 0.78 | CA2 (0.44) | CA2CA1PTGER4NAMPTMAPT | |
| SCHEMBL6674730 | 0.76 | ACHE (0.34) | GLALMNAKDM4E | |
| SCHEMBL6687614 | 0.76 | IDO1 (0.41) | CA2CA1MAPTNQO2ALDH1A1 | |
| SCHEMBL6681075 | 0.76 | NQO2 (0.39) | CA2CA1MAPTNQO2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8771569 | 0.76 | ACHE (0.34) | MAPTTDP1GLAKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | disclosed |
| EP-0798292-A1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | Chugai Seiyaku Kabushiki Kaisha (JP) | 1997-10-01 | — | — | EP | disclosed |