Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6676265 | 0.89 | CA2 (0.40) | CA2CA1NAMPTPARP1PTGER4 | |
| SCHEMBL6675284 | 0.89 | ESRRG (0.42) | CA2CA1NAMPTPTGER4NQO2 | |
| SCHEMBL6674730 | 0.88 | ACHE (0.34) | — | |
| SCHEMBL6682001 | 0.88 | CA1 (0.41) | CA2CA1NAMPTMAPT | |
| Hydrochloric Acid SCHEMBL8771569 | 0.87 | ACHE (0.34) | MAPTTDP1 | |
| SCHEMBL6676118 | 0.84 | CA2 (0.47) | CA2CA1NAMPTPTGER4MAPT | |
| SCHEMBL6681075 | 0.81 | NQO2 (0.39) | CA2CA1NQO2MAPT | |
| SCHEMBL6675306 | 0.80 | NQO2 (0.38) | CA2CA1NQO2MAPT | |
| SCHEMBL6681893 | 0.79 | CA2 (0.43) | CA2CA1NAMPTPARP1PTGER4 | |
| SCHEMBL6687614 | 0.75 | IDO1 (0.41) | CA2CA1NQO2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-A1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | Chugai Seiyaku Kabushiki Kaisha (JP) | 1997-10-01 | — | — | EP | disclosed |