Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13145941 | 0.85 | KDM4E (0.32) | CA2GABRA1GABRB2 | |
| SCHEMBL15449659 | 0.74 | ACHE (0.36) | CA2GABRA1GABRB2 | |
| SCHEMBL13876260 | 0.69 | — | — | |
| SCHEMBL29962993 | 0.66 | HDAC8 (0.30) | — | |
| SCHEMBL12306280 | 0.63 | HDAC8 (0.46) | — | |
| SCHEMBL8276398 | 0.62 | BCHE (0.31) | — | |
| SCHEMBL13876366 | 0.62 | ALDH1A1 (0.34) | CA2 | |
| SCHEMBL378551 | 0.61 | — | — | |
| SCHEMBL28491364 | 0.60 | BCHE (0.31) | — | |
| Hydrochloric Acid SCHEMBL7856022 | 0.59 | TSHR (0.42) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10301272-B2 | Carboxamide or sulfonamide substituted thiazoles and related derivatives as modulators for the orphan nuclear receptor ROR[γ] | PHENEX PHARMACEUTICALS AG (DE) | 2019-05-28 | — | — | US | disclosed |
| US-9964531-B2 | Phenylacetylenes | UNIVERSITY OF OREGON (US) | 2018-05-08 | — | — | US | disclosed |
| US-20150355153-A1 | PHENYLACETYLENES | UNIVERSITY OF OREGON (US) | 2015-12-10 | — | — | US | disclosed |
| US-20150175562-A1 | CARBOXAMIDE OR SULFONAMIDE SUBSTITUTED THIAZOLES AND RELATED DERIVATIVES AS MODULATORS FOR THE ORPHAN NUCLEAR RECEPTOR ROR[GAMMA] | PHENEX PHARMACEUTICALS AG (DE) | 2015-06-25 | — | — | US | disclosed |
| EP-2855440-A1 | CARBOXAMIDE OR SULFONAMIDE SUBSTITUTED THIAZOLES AND RELATED DERIVATIVES AS MODULATORS FOR THE ORPHAN NUCLEAR RECEPTOR ROR[GAMMA] | Phenex Pharmaceuticals AG (DE) | 2015-04-08 | — | — | EP | disclosed |
| US-8841460-B2 | Tunable phenylacetylene hosts | STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF OREGON (US) | 2014-09-23 | — | — | US | disclosed |
| US-20140031559-A1 | TUNABLE PHENYLACETYLENE HOSTS | State of Oregon, acting by and through the State Board of Higher Education on Behalf of University (US) | 2014-01-30 | — | — | US | disclosed |
| WO-2013178362-A1 | CARBOXAMIDE OR SULFONAMIDE SUBSTITUTED THIAZOLES AND RELATED DERIVATIVES AS MODULATORS FOR THE ORPHAN NUCLEAR RECEPTOR ROR[GAMMA] | PHENEX PHARMACEUTICALS AG (DE) | 2013-12-05 | — | — | WO | disclosed |
| EP-1228189-B1 | MICROEMULSION CLEANING COMPOSITION | BAKER HUGHES INC (US) | 2004-10-13 | — | — | EP | disclosed |
| US-6486115-B1 | Microemulsion cleaning composition | BAKER HUGHES INCORPORATED | 2002-11-26 | — | — | US | disclosed |
| EP-1228189-A1 | MICROEMULSION CLEANING COMPOSITION | BAKER HUGHES INCORPORATED (US) | 2002-08-07 | — | — | EP | disclosed |
| WO-2001034760-A1 | MICROEMULSION CLEANING COMPOSITION | BAKER HUGHES INCORPORATED (US) | 2001-05-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150355153-A1 | PHENYLACETYLENES | HDAC10, H1-10, H1-0 | CA2 3121/4885GABRA1 3312/4885GABRB2 3218/4885 |
| US-20140031559-A1 | TUNABLE PHENYLACETYLENE HOSTS | NAA10, OR10J3, CBR3 | CA2 157/4885GABRA1 1137/4885GABRB2 1184/4885 |
| US-20150175562-A1 | CARBOXAMIDE OR SULFONAMIDE SUBSTITUTED THIAZOLES AND RELATED DERIVATIVES AS MODULATORS FOR THE ORPHAN NUCLEAR RECEPTOR ROR[GAMMA] | RORA, RORB, RORC | CA2 304/4885GABRA1 261/4885GABRB2 342/4885 |
| US-10301272-B2 | Carboxamide or sulfonamide substituted thiazoles and related derivatives as modulators for the orphan nuclear receptor ROR[γ] | RORA, RORB, RORC | CA2 343/4885GABRA1 273/4885GABRB2 345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.