Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.39 |
| ▸ | CFD | P00746 | 1/20 | 0.39 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.39 |
| ▸ | GALR2 | O43603 | 1/20 | 0.38 |
| ▸ | GALR1 | P47211 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6685718 | 0.89 | TDP1 (0.48) | EPHX1L3MBTL1TDP1 | |
| SCHEMBL6685688 | 0.77 | KIF11 (0.38) | EPHX1L3MBTL1NPC1RAB9A | |
| SCHEMBL6689992 | 0.73 | CFD (0.41) | EPHX1TAS1R3TAS1R1TAS1R2CFD | |
| SCHEMBL6690874 | 0.72 | TDP1 (0.47) | EPHX1L3MBTL1TDP1 | |
| SCHEMBL6688717 | 0.71 | SMN1; SMN2 (0.50) | L3MBTL1NPC1RAB9A | |
| SCHEMBL6690797 | 0.71 | POLB (0.39) | EPHX1L3MBTL1NPC1RAB9A | |
| SCHEMBL6685642 | 0.70 | CTSS (0.54) | EPHX1L3MBTL1TDP1 | |
| SCHEMBL6686917 | 0.70 | CTSS (0.54) | EPHX1L3MBTL1TDP1 | |
| SCHEMBL6688737 | 0.68 | CTSS (0.47) | L3MBTL1TDP1 | |
| SCHEMBL4796161 | 0.68 | CTSL (0.43) | EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084843-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |