SCHEMBL668681

SCHEMBL668681

[c]1cccc(-c2ccccc2)c1-c1cccc2ccccc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.42
KDM4E B2RXH2 2/20 0.42
ALDH1A1 P00352 2/20 0.42
HPGD P15428 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
TP53 P04637 1/20 0.42
TSHR P16473 1/20 0.42
NFKB1 P19838 1/20 0.42
MAPK1 P28482 1/20 0.42
NFKB2 Q00653 1/20 0.42
RELA Q04206 1/20 0.42
ATM Q13315 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TNF P01375 1/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
MPI P34949 1/20 0.41
SIGMAR1 Q99720 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL669469 0.87 CYP2A6 (0.40) MAPTKDM4EALDH1A1HPGDTDP1
SCHEMBL668822 0.86 ALDH1A1 (0.42) MAPTKDM4EALDH1A1HPGDTDP1
SCHEMBL18258983 0.85 CYP2A6 (0.39) MAPTKDM4EALDH1A1HPGDTDP1
SCHEMBL8406504 0.83 GSTP1 (0.43) MAPTALDH1A1CA12CA1CA2
SCHEMBL11781218 0.81 MAPT (0.40) MAPTKDM4EALDH1A1HPGDTDP1
SCHEMBL646330 0.81 ALDH1A1 (0.42) MAPTKDM4EALDH1A1HPGDTDP1
SCHEMBL18957552 0.79 KDM4E (0.38) MAPTKDM4EALDH1A1HPGDTDP1
SCHEMBL9614637 0.79 ALDH1A1 (0.50) KDM4EALDH1A1HPGDTSHRHSD17B10
SCHEMBL8434859 0.79 CYP2A6 (0.50) KDM4EALDH1A1TDP1TSHRATM
SCHEMBL3841865 0.79 CYP1A2 (0.50) MAPTKDM4EALDH1A1HPGDTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240172559-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM,LTD. (KR) 2024-05-23 US claimed
US-20240172559-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM,LTD. (KR) 2024-05-23 US disclosed
CN-116671280-A Organic light emitting device 株式会社LG化学 2023-08-29 CN disclosed
WO-2023003436-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2023-01-26 WO disclosed
CN-109790131-B Heterocyclic compound and organic light-emitting device comprising same 株式会社LG化学 2022-09-06 CN disclosed
CN-112812024-B Organic compound, application and organic electroluminescent device using organic compound 陕西莱特迈思光电材料有限公司 2022-03-29 CN disclosed
US-11251377-B2 Organic light emitting device LG CHEM, LTD. (KR) 2022-02-15 US disclosed
US-11189800-B2 Heterocyclic compound and organic light emitting device comprising the same LG CHEM, LTD. (KR) 2021-11-30 US disclosed
CN-109311844-B Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component 东曹株式会社 2021-07-20 CN disclosed
WO-2021136055-A1 NITROGEN-CONTAINING ORGANIC COMPOUND, USE THEREOF, AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 陕西莱特光电材料股份有限公司 2021-07-08 WO disclosed
US-20100187511-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2010-07-29 US disclosed
EP-2159217-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME Idemitsu Kosan Co., Ltd. (JP) 2010-03-03 EP disclosed
EP-2124270-A1 ORGANIC EL DEVICE Idemitsu Kosan Co., Ltd. (JP) 2009-11-25 EP disclosed
EP-2085371-A1 FLUORANTHENE COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE USING THE FLUORANTHENE COMPOUND, AND ORGANIC ELECTROLUMINESCENT MATERIAL-CONTAINING SOLUTION Idemitsu Kosan Co., Ltd. (JP) 2009-08-05 EP disclosed
US-20090167156-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2009-07-02 US disclosed
US-20090015144-A1 FLUORANTHENE COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME, AND SOLUTION CONTAINING ORGANIC ELECTROLUMINESCENCE MATERIAL IDEMITSU KOSAN CO., LTD. (JP) 2009-01-15 US disclosed
EP-2008992-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME Idemitsu Kosan Co., Ltd. (JP) 2008-12-31 EP disclosed
EP-1990844-A1 ORGANIC ELECTROLUMINESCENT DEVICE Idemitsu Kosan Co., Ltd. (JP) 2008-11-12 EP disclosed
US-20080004445-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2008-01-03 US disclosed
US-20070243411-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2007-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080004445-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME TYR, MAOA, PRDM9 MAPT 232/4885KDM4E 126/4885ALDH1A1 291/4885
US-20240172559-A1 ORGANIC LIGHT EMITTING DEVICE CRY1, CRY2, CYP1A1 MAPT 1314/4885KDM4E 3863/4885ALDH1A1 9/4885
US-11189800-B2 Heterocyclic compound and organic light emitting device comprising the same CRY1, CYBA, CYP1B1 MAPT 1798/4885KDM4E 2736/4885ALDH1A1 33/4885
US-20090015144-A1 FLUORANTHENE COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME, AND SOLUTION CONTAINING ORGANIC ELECTROLUMINESCENCE MATERIAL LEF1, ESD, AFF2 MAPT 1316/4885KDM4E 1881/4885ALDH1A1 422/4885
US-20100187511-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME TYR, DDC, OCIAD2 MAPT 136/4885KDM4E 261/4885ALDH1A1 428/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.