Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2B | Q02880 | 2/20 | 0.36 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | GSR | P00390 | 2/20 | 0.34 |
| ▸ | GHSR | Q92847 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 6/20 | 0.33 |
| ▸ | CA2 | P00918 | 6/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6686636 | 0.83 | MAPT (0.42) | CA1CA2CA9CA12 | |
| SCHEMBL6688710 | 0.81 | POLB (0.43) | CA1CA2CA12 | |
| SCHEMBL6687560 | 0.81 | MAPT (0.38) | — | |
| SCHEMBL6687217 | 0.77 | PARP1 (0.42) | — | |
| SCHEMBL4799004 | 0.73 | TGM2 (0.38) | TGM2GHSRCA1CA2CA9 | |
| SCHEMBL13589541 | 0.70 | GSR (0.50) | TOP2BGSRGHSRCA1CA2 | |
| SCHEMBL6690542 | 0.67 | RORC (0.41) | GHSRCA2 | |
| SCHEMBL14624916 | 0.65 | CA12 (0.49) | TGM2GSRCA1CA2CA9 | |
| SCHEMBL13589540 | 0.64 | CA1 (0.45) | TGM2GHSRCA1CA2CA9 | |
| SCHEMBL8212136 | 0.64 | GHSR (0.47) | TGM2GHSRCA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084843-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |