Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6686636 | 0.88 | MAPT (0.42) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL6688710 | 0.86 | POLB (0.43) | MAPTMEN1KMT2AHTTL3MBTL1 | |
| SCHEMBL6689081 | 0.81 | TOP2B (0.36) | — | |
| SCHEMBL4798876 | 0.77 | ALDH1A1 (0.39) | MAPTAPOBEC3AAPOBEC3GMEN1KMT2A | |
| SCHEMBL6687217 | 0.75 | PARP1 (0.42) | MEN1KMT2A | |
| SCHEMBL6687352 | 0.67 | MAPT (0.45) | MAPTAPOBEC3AAPOBEC3GMEN1KMT2A | |
| SCHEMBL4798680 | 0.64 | CTSS (0.48) | POLB | |
| SCHEMBL4800097 | 0.64 | CTSK (0.42) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL2476390 | 0.62 | GLA (0.69) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL6688714 | 0.62 | POLB (0.47) | MAPTMEN1KMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084843-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |