Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.34 |
| ▸ | PYGL | P06737 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 2/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.31 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6685697 | 0.96 | TRPV1 (0.35) | TRPV1IDO1NQO2MTNR1AMTNR1B | |
| SCHEMBL6687531 | 0.94 | TRPV1 (0.34) | TRPV1PYGLIDO1NQO2MTNR1A | |
| SCHEMBL6686236 | 0.93 | GRM7 (0.38) | TRPV1PYGLGRM7 | |
| SCHEMBL6688201 | 0.86 | FAAH (0.43) | TRPV1FAAHPTGS2 | |
| SCHEMBL6686987 | 0.80 | CTSL (0.42) | PYGL | |
| SCHEMBL6689091 | 0.79 | CTSL (0.41) | — | |
| SCHEMBL6688775 | 0.78 | CTSS (0.41) | GRM7 | |
| SCHEMBL6689089 | 0.78 | KMT2A (0.42) | TRPV1 | |
| SCHEMBL6686227 | 0.78 | CTSS (0.40) | TRPV1 | |
| SCHEMBL6690788 | 0.78 | CTSD (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084843-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |