Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1F | P30939 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6690788 | 0.86 | CTSD (0.38) | KMT2AALDH1A1EPHX2NAMPTCTSS | |
| SCHEMBL6686227 | 0.85 | CTSS (0.40) | ALDH1A1CTSLTRPV1CTSSPKM | |
| SCHEMBL6689428 | 0.84 | MEN1 (0.41) | KMT2AALDH1A1MEN1 | |
| SCHEMBL6686987 | 0.84 | CTSL (0.42) | KMT2AALDH1A1CTSLCTSSMEN1 | |
| SCHEMBL6689091 | 0.83 | CTSL (0.41) | KMT2AALDH1A1SMN1; SMN2CTSLCTSS | |
| SCHEMBL6692878 | 0.81 | MEN1 (0.39) | KMT2APRMT5MEN1 | |
| SCHEMBL6690045 | 0.81 | ALDH1A1 (0.51) | KMT2AALDH1A1SMN1; SMN2TSHREPHX2 | |
| SCHEMBL6685697 | 0.80 | TRPV1 (0.35) | HTR1AHTR1DHTR1FCTSLTRPV1 | |
| SCHEMBL6686236 | 0.79 | GRM7 (0.38) | KMT2ATSHRTRPV1MEN1 | |
| SCHEMBL6689424 | 0.78 | TRPV1 (0.34) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084843-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |