Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.35 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1F | P30939 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6689424 | 0.96 | TRPV1 (0.34) | TRPV1GRM7IDO1NQO2MTNR1A | |
| SCHEMBL6687531 | 0.96 | TRPV1 (0.34) | TRPV1IDO1NQO2MTNR1AMTNR1B | |
| SCHEMBL6686236 | 0.95 | GRM7 (0.38) | TRPV1GRM7 | |
| SCHEMBL6688201 | 0.89 | FAAH (0.43) | TRPV1 | |
| SCHEMBL6686987 | 0.82 | CTSL (0.42) | CTSLL3MBTL1 | |
| SCHEMBL6689091 | 0.81 | CTSL (0.41) | CTSLL3MBTL1 | |
| SCHEMBL6689089 | 0.80 | KMT2A (0.42) | TRPV1CTSLHTR1AHTR1DHTR1F | |
| SCHEMBL6686227 | 0.80 | CTSS (0.40) | TRPV1CTSL | |
| SCHEMBL6690788 | 0.80 | CTSD (0.38) | — | |
| SCHEMBL5505729 | 0.78 | OPRL1 (0.34) | IDO1CTSLHTR1AHTR1DHTR1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084843-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |