Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM7 | Q14831 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6685697 | 0.95 | TRPV1 (0.35) | GRM7TRPV1 | |
| SCHEMBL6689424 | 0.93 | TRPV1 (0.34) | GRM7TRPV1PYGL | |
| SCHEMBL6687531 | 0.93 | TRPV1 (0.34) | TSHRTRPV1PYGL | |
| SCHEMBL6688201 | 0.90 | FAAH (0.43) | MEN1KMT2ATRPV1 | |
| SCHEMBL6686227 | 0.83 | CTSS (0.40) | TRPV1 | |
| SCHEMBL6690648 | 0.82 | NMT2 (0.45) | GRM7 | |
| SCHEMBL6686987 | 0.82 | CTSL (0.42) | MEN1KMT2APYGL | |
| SCHEMBL6689091 | 0.81 | CTSL (0.41) | MEN1KMT2A | |
| SCHEMBL6690788 | 0.80 | CTSD (0.38) | TDP1KMT2A | |
| SCHEMBL6689089 | 0.79 | KMT2A (0.42) | TSHRMEN1KMT2ATRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084843-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |