Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.37 |
| ▸ | RORC | P51449 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6692878 | 0.91 | MEN1 (0.39) | MEN1KMT2ARAB9AHRH3MAPT | |
| SCHEMBL6689089 | 0.84 | KMT2A (0.42) | MEN1KMT2AALDH1A1 | |
| SCHEMBL6686227 | 0.84 | CTSS (0.40) | ALDH1A1KDM4E | |
| SCHEMBL6690788 | 0.80 | CTSD (0.38) | KMT2AALDH1A1 | |
| SCHEMBL6686987 | 0.79 | CTSL (0.42) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL6689091 | 0.78 | CTSL (0.41) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL6685697 | 0.75 | TRPV1 (0.35) | — | |
| SCHEMBL6686236 | 0.74 | GRM7 (0.38) | MEN1KMT2A | |
| SCHEMBL6686187 | 0.74 | CTSL (0.46) | — | |
| SCHEMBL6687345 | 0.73 | CTSS (0.45) | MEN1KMT2ARAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084843-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |