Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6691606 | 0.91 | HSD17B2 (0.41) | MAPTMAPK1HTTLMNASMN1; SMN2 | |
| SCHEMBL6678578 | 0.87 | MAPT (0.42) | MAPTMAPK1HTTLMNASMN1; SMN2 | |
| SCHEMBL6679654 | 0.83 | TRPM8 (0.45) | MAPTMAPK1HTTLMNASMN1; SMN2 | |
| SCHEMBL6698055 | 0.80 | ALDH1A1 (0.42) | MAPTMAPK1HTTLMNASMN1; SMN2 | |
| SCHEMBL6689149 | 0.76 | GPR139 (0.39) | MAPTMAPK1HTTLMNASMN1; SMN2 | |
| SCHEMBL6677495 | 0.74 | SMN1; SMN2 (0.48) | MAPTMAPK1LMNASMN1; SMN2MEN1 | |
| SCHEMBL4916663 | 0.70 | FGFR2 (0.37) | MAPTMAPK1HTTSMN1; SMN2MEN1 | |
| SCHEMBL6693365 | 0.69 | ALDH1A1 (0.59) | LMNAMEN1KMT2AALDH1A1GAA | |
| SCHEMBL14082967 | 0.68 | TRPV1 (0.66) | MAPTMEN1KMT2AALDH1A1DRD4 | |
| SCHEMBL3640854 | 0.66 | MAPT (0.49) | MAPTHTTLMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | claimed |