Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TACR3 | P29371 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6683423 | 0.86 | MAPT (0.48) | ALDH1A1KDM4ELMNAMAPTSMN1; SMN2 | |
| SCHEMBL6677935 | 0.85 | KCNK3 (0.40) | ALDH1A1KDM4ELMNAHTTMAPT | |
| SCHEMBL6689149 | 0.85 | GPR139 (0.39) | ALDH1A1KDM4ELMNAHTTMAPT | |
| SCHEMBL6678578 | 0.83 | MAPT (0.42) | ALDH1A1KDM4ELMNAHTTMAPT | |
| SCHEMBL6691606 | 0.83 | HSD17B2 (0.41) | ALDH1A1LMNAHTTMAPTSMN1; SMN2 | |
| SCHEMBL6679654 | 0.81 | TRPM8 (0.45) | ALDH1A1LMNAHTTMAPTSMN1; SMN2 | |
| SCHEMBL6689991 | 0.80 | MAPT (0.41) | ALDH1A1KDM4ELMNAHTTMAPT | |
| SCHEMBL28830814 | 0.73 | NPSR1 (0.55) | ALDH1A1LMNAMAPTRAB9ANPC1 | |
| SCHEMBL4916663 | 0.70 | FGFR2 (0.37) | ALDH1A1KDM4EHTTMAPTSMN1; SMN2 | |
| SCHEMBL22897202 | 0.65 | CAPN1 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | claimed |