Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TACR3 | P29371 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6698055 | 0.85 | ALDH1A1 (0.42) | MEN1KMT2AKDM4EMAPTLMNA | |
| SCHEMBL6683423 | 0.83 | MAPT (0.48) | MEN1KMT2AKDM4EMAPTLMNA | |
| SCHEMBL6677935 | 0.81 | KCNK3 (0.40) | HSD17B2MEN1KMT2AKDM4EMAPT | |
| SCHEMBL6678578 | 0.81 | MAPT (0.42) | MEN1KMT2AKDM4EMAPTLMNA | |
| SCHEMBL6691606 | 0.78 | HSD17B2 (0.41) | HSD17B2MEN1KMT2AMAPTLMNA | |
| SCHEMBL6689991 | 0.76 | MAPT (0.41) | MEN1KMT2AKDM4EMAPTLMNA | |
| SCHEMBL6679654 | 0.73 | TRPM8 (0.45) | MEN1KMT2AMAPTLMNANPSR1 | |
| SCHEMBL4916663 | 0.68 | FGFR2 (0.37) | MEN1KMT2AKDM4EMAPTHTT | |
| SCHEMBL6355765 | 0.65 | GPR139 (0.74) | GPR139P2RX7TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL16714289 | 0.64 | MAPT (0.38) | MEN1KMT2AKDM4EMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | claimed |
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | disclosed |