SCHEMBL6690712

SCHEMBL6690712

CCc1ccc(Cc2cnc(OC)nc2O)cc1

nearest known ligand 0.48

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DHFR P00374 3/20 0.38
PDE10A Q9Y233 2/20 0.37
HTT P42858 1/20 0.36
PKM P14618 1/20 0.36
CYP19A1 P11511 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10970314 0.86 BCL2 (0.41)
SCHEMBL6688779 0.84 RXRA (0.44)
SCHEMBL6688782 0.75 ALDH1A1 (0.34)
SCHEMBL19771688 0.74 FTO (0.36)
SCHEMBL10967957 0.74 LMNA (0.43) PDE10AHTT
SCHEMBL4279803 0.69 ALOX5 (0.38) PDE10A
SCHEMBL30783210 0.69 FAAH (0.41) DHFR
SCHEMBL6686848 0.69 ALDH1A1 (0.43) HTT
SCHEMBL4592146 0.69 CXCR4 (0.46)
SCHEMBL1687460 0.68 FTO (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004099230-A1 MONOSACCHARIDE COMPOUNDS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-11-18 WO disclosed